Evidence map›Paper›PMID 40250029›Full record

ArticleGynecologic oncology2025

Disparities in facility-level adoption of minimally invasive interval debulking surgery for advanced ovarian cancer.

Roni Nitecki Wilke, Chi-Fang Wu, Alexa Kanbergs, Alexandra S Bercow, Nuria Agusti, David Viveros-Carreño, Abigail S Zamorano, Jose Alejandro Rauh-Hain, Alexander Melamed

Abstract read
In one paragraph

Article in Gynecologic oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Current oncology (Toronto, Ont.) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Roni Nitecki WilkeDepartment of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: rnitecki@mdanderson.org.
Chi-Fang WuDepartment of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Alexa KanbergsDepartment of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Alexandra S BercowDepartment of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Nuria AgustiDepartment of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
David Viveros-CarreñoClínica Universitaria Colombia, Bogotá, Colombia; Unidad Ginecología Oncológica, Grupo de Investigación GIGA, Centro de Tratamiento e Investigación sobre Cáncer Luis Carlos Sarmiento Angulo, Bogotá, Colombia.
Abigail S ZamoranoDivision of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Health Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Jose Alejandro Rauh-HainDepartment of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Alexander MelamedDepartment of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
Training of Academic Gynecologic OncologistsT32CA101642 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI ANIL K SOOD, Kathleen Schmeler · 2005 to 2026
$9.2M
Obstetrical and Oncological Outcomes Among Reproductive Age Women with Gynecological and Breast CancerK08CA234333 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI RAUH-HAIN, JOSE ALEJANDRO · 2018 to 2022
$1.2M
NCI NIH HHS K08 CA234333NCI NIH HHS P30 CA016672NCI NIH HHS T32 CA101642
6 · The paper itself

Abstract

objectiveFacility-level disparities in the adoption of minimally invasive (MIS) interval debulking surgery (IDS) among Commission-on-Cancer-accredited programs in the United States were examined.

methodsPatients with stage IIIC or IV epithelial ovarian cancer (2010-2021) who received neoadjuvant chemotherapy and IDS were identified in the National Cancer Database. Analytical periods were categorized as the preadoption (2010 to 2014) and postadoption (2015 to 2021) periods. We defined "Adopter" facilities as those that significantly increased their use of MIS for IDS after 2015 and "non-adopter" facilities as those that restricted the use of this approach after 2015. Hospital-level variation in the use of IDS via MIS was estimated and then adopter programs were matched with non-adopter programs. We examined the associations between characteristics of interest-Black-serving (top 5 %), serving a high proportion of uninsured patients (top 5 %), high-volume (top quartile), and academic-and the tendency to perform IDS using logistic regressions.

resultsWe identified 5464 patients treated in 141 adopter facilities and 4820 patients treated in 141 non-adopter facilities. Adopter facilities were less likely than non-adopter facilities to be Black-serving (odds ratio [OR], 0.66; 95 % CI, 0.55-0.79; P < 0.001) and to have a high proportion of uninsured patients (OR, 0.73; 95 % CI, 0.61-0.87, P < 0.001) and more likely to be high-volume centers (OR, 1.48; 95 % CI, 1.35-1.60; P < 0.001) and academic institutions (OR, 1.89; 95 % CI, 1.74-2.04, P < 0.001).

conclusionsAs MIS IDS is adopted in the United States, minoritized patients may have unequal access depending on where they receive care.

Indexed as

Carcinoma, Ovarian EpithelialCytoreduction Surgical ProceduresHealthcare DisparitiesMinimally Invasive Surgical ProceduresOvarian NeoplasmsAdultAgedFemaleHumansMiddle AgedNeoadjuvant TherapyNeoplasm StagingUnited StatesDispartiesInterval debulking surgeryMinimally invasive surgery

Identifiers

PMID40250029
PMCPMC12520625

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.