Evidence map›Paper›PMID 40249940›Full record

SynthesisJournal of medical Internet research2025

Diagnosis Test Accuracy of Artificial Intelligence for Endometrial Cancer: Systematic Review and Meta-Analysis.

Longyun Wang, Zeyu Wang, Bowei Zhao, Kai Wang, Jingying Zheng, Lijing Zhao

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Longyun Wang *Department of Rehabilitation, School of Nursing, Jilin University, Changchun, China.ORCID https://orcid.org/0009-0000-5865-5104
Zeyu Wang *Department of Rehabilitation, School of Nursing, Jilin University, Changchun, China.ORCID https://orcid.org/0000-0002-1870-3447
Bowei ZhaoDepartment of Rehabilitation, School of Nursing, Jilin University, Changchun, China.ORCID https://orcid.org/0009-0000-4155-1552
Kai WangDepartment of Rehabilitation, School of Nursing, Jilin University, Changchun, China.ORCID https://orcid.org/0009-0000-2948-406X
Jingying Zheng *Department of Gynecology and Obstetrics, The Second Hospital of Jilin University, Changchun, China.ORCID https://orcid.org/0009-0003-2003-2499
Lijing Zhao *Department of Rehabilitation, School of Nursing, Jilin University, Changchun, China.ORCID https://orcid.org/0000-0002-3190-7399

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndometrial cancer is one of the most common gynecological tumors, and early screening and diagnosis are crucial for its treatment. Research on the application of artificial intelligence (AI) in the diagnosis of endometrial cancer is increasing, but there is currently no comprehensive meta-analysis to evaluate the diagnostic accuracy of AI in screening for endometrial cancer.

objectiveThis paper presents a systematic review of AI-based endometrial cancer screening, which is needed to clarify its diagnostic accuracy and provide evidence for the application of AI technology in screening for endometrial cancer.

methodsA search was conducted across PubMed, Embase, Cochrane Library, Web of Science, and Scopus databases to include studies published in English, which evaluated the performance of AI in endometrial cancer screening. A total of 2 independent reviewers screened the titles and abstracts, and the quality of the selected studies was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool. The certainty of the diagnostic test evidence was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system.

resultsA total of 13 studies were included, and the hierarchical summary receiver operating characteristic model used for the meta-analysis showed that the overall sensitivity of AI-based endometrial cancer screening was 86% (95% CI 79%-90%) and specificity was 92% (95% CI 87%-95%). Subgroup analysis revealed similar results across AI type, study region, publication year, and study type, but the overall quality of evidence was low.

conclusionsAI-based endometrial cancer screening can effectively detect patients with endometrial cancer, but large-scale population studies are needed in the future to further clarify the diagnostic accuracy of AI in screening for endometrial cancer.

trial registrationPROSPERO CRD42024519835; https://www.crd.york.ac.uk/PROSPERO/view/CRD42024519835.

Indexed as

Artificial IntelligenceEndometrial NeoplasmsEarly Detection of CancerFemaleHumansROC CurveSensitivity and Specificityartificial intelligencedeep learningdiagnostic test accuracyendometrial cancermachine learningmeta-analysissystematic review

Identifiers

PMID40249940
PMCPMC12048793

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.