Evidence map›Paper›PMID 40249785›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Esmerina Tili, Teresa L Commisso, Veronica Balatti, Jean-Jacques Michaille, Gerard J Nuovo, Carlo M Croce

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Loss of ICOSL expression in the progression to cervical carcinoma.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Nasopharyngeal carcinoma: a model cancer to understand tumor rejection.Signal transduction and targeted therapy · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Esmerina TiliDepartment of Anesthesiology, Wexner Medical Center, College of Medicine, The Ohio State University, Columbus, OH 43210.
Teresa L CommissoDepartment of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
Veronica BalattiDepartment of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
Jean-Jacques MichailleDepartment of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
Gerard J NuovoGnome, Powell, OH 43065.
Carlo M CroceDepartment of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.ORCID 0000-0003-3788-1457

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Daniel G. Stover · 1985 to 2026
$132.3M
Cancer Gene Discovery to Identify Targetable TargetsR35CA197706 · NCI · OHIO STATE UNIVERSITY · PI CROCE, CARLO M · 2015 to 2021
$6.4M
CLL Global Research Foundation (CLLGRF) AWD-115284CLL Global Research Foundation (CLLGRF) AWD-116510NCI NIH HHS P30 CA016058NCI NIH HHS R35 CA197706R35 CA197706
6 · The paper itself

Abstract

Elevated

Indexed as

Gene Expression Regulation, NeoplasticHistocompatibility Antigens Class ILymphoma, Large B-Cell, DiffuseMicroRNAsAnimalsCell Line, TumorHumansInducible T-Cell Co-Stimulator LigandInducible T-Cell Co-Stimulator ProteinMiceHistocompatibility Antigens Class IICOSLG protein, humanInducible T-Cell Co-Stimulator LigandInducible T-Cell Co-Stimulator ProteinMicroRNAsMIRN155 microRNA, humanDLBCLICOSLlymphomaMHC-ImicroRNA

Identifiers

PMID40249785
PMCPMC12036973

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.