Evidence map›Paper›PMID 40249532›Full record

ArticleJapanese journal of ophthalmology2025

Choroidal circulation time by wide-field indocyanine green angiography in central serous chorioretinopathy.

Akiyuki Kawamura, Ryusaburo Mori, Koji Tanaka, Yu Wakatsuki, Kyoko Fujita, Hiroyuki Nakashizuka

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Article in Japanese journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Akiyuki KawamuraDivision of Ophthalmology, Department of Visual Science, Nihon University Hospital, Nihon University School of Medicine, 1-6, Kanda-Surugadai Chiyodaku, Tokyo, 101-8309, Japan.
Ryusaburo MoriDivision of Ophthalmology, Department of Visual Science, Nihon University Hospital, Nihon University School of Medicine, 1-6, Kanda-Surugadai Chiyodaku, Tokyo, 101-8309, Japan. mori.ryusaburo@nihon-u.ac.jp.
Koji TanakaDivision of Ophthalmology, Department of Visual Science, Nihon University Hospital, Nihon University School of Medicine, 1-6, Kanda-Surugadai Chiyodaku, Tokyo, 101-8309, Japan.
Yu WakatsukiDivision of Ophthalmology, Department of Visual Science, Nihon University Hospital, Nihon University School of Medicine, 1-6, Kanda-Surugadai Chiyodaku, Tokyo, 101-8309, Japan.
Kyoko FujitaAichi Medical University, Nagakute, Japan.
Hiroyuki NakashizukaDivision of Ophthalmology, Department of Visual Science, Nihon University Hospital, Nihon University School of Medicine, 1-6, Kanda-Surugadai Chiyodaku, Tokyo, 101-8309, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAsymmetric dilated vortex veins (ADVV) extending continuously to the vortex ampullae seen on Indocyanine green angiography (ICGA) findings, are thought to indicate choroidal venous congestion in central serous chorioretinopathy (CSC). In addition, the sclera is thickened compared to normal eyes, suggesting that obstruction of the scleral passage is the pathophysiological mechanism of CSC. The purpose of this study was to examine the choroidal circulation in and around the vortex vein ampulla. STUDY

designSingle-center retrospective study.

methodsThe subjects were 23 CSC eyes with macular central serous detachment (SRD) undergoing wide-field ICGA with Spectralis

resultsThe mean choroidal circulation time was 4.44 seconds for the superior temporal side and 4.33 seconds for the inferior temporal side, with no significant difference (p=0.494). The mean choroidal circulation time was 3.89 seconds on the ADVV side and 4.88 seconds on the non-ADVV side, with a shorter mean circulation time on the ADVV side (p=0.00005). In 21 of 23 eyes, there was a time difference in the filling of the choroidal veins entering the vortex vein ampulla.

conclusionOn the side of the ADVV, no obstruction to the passage of the sclera is thought to have occurred.

Indexed as

Central Serous ChorioretinopathyChoroidFluorescein AngiographyIndocyanine GreenAdultAgedBlood Flow VelocityColoring AgentsFemaleFollow-Up StudiesFundus OculiHumansMaleMiddle AgedRegional Blood FlowRetrospective StudiesColoring AgentsIndocyanine GreenAsymmetric dilated vortex veinCentral serous chorioretinopathyChoroidal vascular hyperpermeabilityIndocyanine green angiographyVortex veins ampulla

Identifiers

PMID40249532

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.