Evidence map›Paper›PMID 40249502›Full record

ReviewJournal of ultrasound2025

Multiparametric ultrasound in acute scrotum: a comprehensive review with special emphasis on contrast-enhanced ultrasound.

Maria Laura Schillirò, Valeria Lonardo, Francesca Iacobellis, Martina Caruso, Costanza Camillo, Chiara D'Errico, Francesco Verde, Francesco Muto, Giuseppina Dell'Aversano Orabona, Chiara Rinaldo and 8 more

Abstract readReview
In one paragraph

Review in Journal of ultrasound, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Maria Laura Schillirò *Department of General and Emergency Radiology, Antonio Cardarelli" Hospital, 80131, Naples, Italy. marialaura.schilliro@aocardarelli.it.
Valeria Lonardo *Advanced Biomedical Sciences Department, University of Naples Federico II, Naples, Italy. v.lonardoc@gmail.com.ORCID http://orcid.org/0009-0008-6805-6031
Francesca Iacobellis *Department of General and Emergency Radiology, Antonio Cardarelli" Hospital, 80131, Naples, Italy.
Martina Caruso *Department of General and Emergency Radiology, Antonio Cardarelli" Hospital, 80131, Naples, Italy.
Costanza CamilloDepartment of General and Emergency Radiology, Antonio Cardarelli" Hospital, 80131, Naples, Italy.
Chiara D'ErricoDepartment of General and Emergency Radiology, Antonio Cardarelli" Hospital, 80131, Naples, Italy.
Francesco VerdeDepartment of General and Emergency Radiology, Antonio Cardarelli" Hospital, 80131, Naples, Italy.
Francesco MutoDepartment of General and Emergency Radiology, Antonio Cardarelli" Hospital, 80131, Naples, Italy.
Giuseppina Dell'Aversano OrabonaDepartment of General and Emergency Radiology, Antonio Cardarelli" Hospital, 80131, Naples, Italy.
Chiara RinaldoDepartment of General and Emergency Radiology, Antonio Cardarelli" Hospital, 80131, Naples, Italy.
Dario GrimaldiDepartment of General and Emergency Radiology, Antonio Cardarelli" Hospital, 80131, Naples, Italy.
Vittorio SabatinoDepartment of General and Emergency Radiology, Antonio Cardarelli" Hospital, 80131, Naples, Italy.
Enrico ScaranoDepartment of Radiology, "San Carlo" Hospital, 85100, Potenza, Italy.
Maurizio CarrinoDepartment of Andrology "Antonio Cardarelli" Hospital, 80131, Naples, Italy.
Luigi PucciDepartment of Andrology "Antonio Cardarelli" Hospital, 80131, Naples, Italy.
Vito CantisaniDepartment of Radiological Sciences, Oncology and Pathology, Policlinico Umberto I, Sapienza University of Rome, 00161, Rome, Italy.
Gianfranco ValloneDepartment of Life and Health, University of Molise "V. Tiberio2, Campobasso, Italy.
Marco Di Serafino *Department of General and Emergency Radiology, Antonio Cardarelli" Hospital, 80131, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute scrotum poses diagnostic challenges due to its diverse etiology and potential severity. Multiparametric ultrasound has proven to be a fundamental and valuable imaging modality in this context, improving early-phase sensitivity through various techniques, including B-Mode, color Doppler, power Doppler, pulsed Doppler, microflow studies, and elastography. In this context, Contrast-Enhanced Ultrasound (CEUS) emerges as a rapid, safe, and valuable tool in enhancing diagnostic accuracy and therapeutic decisions for acute scrotal conditions. This study involves a detailed analysis of various ultrasound imaging techniques and investigates the optimal circumstances and methods for employing CEUS in emergency situations to improve diagnostic accuracy and therapeutic decisions. Multiparametric ultrasound plays a crucial role in diagnosing various pathologies, including testicular torsion, appendage torsion, inflammation, ischemia/infarction, and trauma. CEUS provides real-time assessment of vascular perfusion, aiding in early diagnosis and accurate characterization of scrotal pathologies and significantly reducing the need for unnecessary surgical interventions, especially in trauma cases. Its role in differentiating between various pathologies and guiding therapeutic decisions underscores its importance in clinical practice, contributing significantly to improve patient outcomes.

Indexed as

Contrast MediaGenital Diseases, MaleImage EnhancementScrotumAcute DiseaseHumansMaleUltrasonographyContrast MediaAcute scrotumContrast-enhanced ultrasound (CEUS)Multiparametric ultrasoundTesticular infarctionTesticular inflammationTesticular torsion

Identifiers

PMID40249502
PMCPMC12145392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.