ArticleThe Journal of experimental medicine2025
Hiding in plain sight: A new lymphoid organ discovered in zebrafish.
Article in The Journal of experimental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Resolving the cellular profile of germinal center-analogous microstructures in zebrafish.Frontiers in immunology · 2026Article
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Authors and funding
2 authors.
Funding
Abstract
A small, unassuming, fleshy lobe at the base of the pectoral fin of fish has long been overlooked by scientists. In this issue of JEM, Castranova et al. (https://doi.org/10.1084/jem.20241435) describe this structure as a new secondary lymphoid organ. Translucent and externally located, the axillary lymphoid organ (ALO) shares striking structural similarities with mammalian secondary lymphoid organs. Due to its position and optical accessibility, the zebrafish ALO permitted noninvasive, high-resolution imaging of immune cell dynamics in live animals. These studies revealed likely interactions between T, B, and macrophage cells, arguing that the ALO may function in adaptive immune cell activation and provide a nexus for immune cell trafficking and communication.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.