ArticleMacromolecular rapid communications2025
Chloromethane-Enabled Quaternization of Linear Polyglycerol Amines and Their Application as Antibacterial Agents.
Article in Macromolecular rapid communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Mechanism and Molecular Design Principles of Cationic Surfactants: From Charge-Driven Membrane Interactions to Next-Generation Quaternary Ammonium Compounds.ChemMedChem · 2026Review
- Chloromethane-Enabled Quaternization of Linear Polyglycerol Amines and Their Application as Antibacterial Agents.Macromolecular rapid communications · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
In this study, the safe and scalable N-methylation of primary amines in a linear polyglycerol (LPG) backbone structure is reported with altering molecular weight using gaseous chloromethane for the generation of quaternary ammonium groups. All polymers are subsequently analyzed for their antibacterial and antibiofilm properties against drug-resistant Staphylococcus aureus (S. aureus), showing that the implementation of quaternary ammonium groups to a polymer backbone structure is an efficient way to generate new antimicrobial agents. Thereby, the molecular weight of the polymer backbone structure strongly correlates to its antibacterial effect and can be altered depending on the desired application.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.