ArticleProtein science : a publication of the Protein Society2025
BioSpring: An elastic network framework for interactive exploration of macromolecular mechanics.
Article in Protein science : a publication of the Protein Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- BioSpring: An elastic network framework for interactive exploration of macromolecular mechanics.Protein science : a publication of the Protein Society · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
BioSpring is an innovative tool for interactive molecular modeling and simulation, designed to explore the dynamics of biological structures in real time. Using an augmented elastic network model, the BioSpring framework enables researchers to intuitively examine complex biomolecules, and it combines real-time feedback with the user's experience. This capability makes it ideal for initial analysis of molecular systems, protein-protein and protein-DNA docking, protein mechanics, and protein-membrane interactions. The multi-resolution modeling approach combines accuracy and efficiency, supporting user-driven analysis of molecular interactions, conformational flexibility, and structural mechanics. This framework improves upon traditional methods in terms of robustness, accessibility, and ease of use, while requiring only modest computational resources and enabling a fast turnaround time to obtain initial results. It provides insights into molecular function and dynamics that advance the field of structural biology. Source code, executables, and examples for the BioSpring simulation engine are available at https://biospring.mol3d.tech.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.