Evidence map›Paper›PMID 40249002›Full record

ArticleMovement disorders clinical practice2025

Stimulation-Induced Dyskinesia in STN DBS Patients.

Carolina Candeias da Silva, Wilson K W Fung, Duha M Al-Shorafat, Aaron Loh, Brendan Santyr, Suneil K Kalia, Andres M Lozano, Alfonso Fasano

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Movement disorders clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carolina Candeias da SilvaEdmond J. Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0003-2661-779X
Wilson K W FungEdmond J. Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-7169-4175
Duha M Al-ShorafatEdmond J. Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Toronto, Ontario, Canada.
Aaron LohDivision of Neurosurgery, University of Toronto, Toronto, Ontario, Canada.
Brendan SantyrDivision of Neurosurgery, University of Toronto, Toronto, Ontario, Canada.
Suneil K KaliaDivision of Neurosurgery, University of Toronto, Toronto, Ontario, Canada.
Andres M LozanoDivision of Neurosurgery, University of Toronto, Toronto, Ontario, Canada.
Alfonso FasanoEdmond J. Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Division of Neurology, University of Toronto, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-5346-0180

Funding

University Health NetworkUniversity of Toronto
6 · The paper itself

Abstract

backgroundStimulation-induced dyskinesia (SID) is a poorly studied and usually transient manifestation of subthalamic deep brain stimulation (STN DBS) for Parkinson's disease (PD), which can be troubling for patients.

objectivesThe aim of our study was to describe the features and management of SID in PD patients undergoing STN DBS.

methodsWe conducted a retrospective study among 86 STN DBS patients. Clinical features and volume of tissue activated (VTA) were correlated to SID occurrence.

resultsSID was identified in 28 (32.6%) patients and persisted for 6 months in six patients (7.0%). VTA overlap with the right motor STN was associated (P < 0.02) with SID. Weaning dopaminergic drugs and reducing the DBS amplitude were the most used strategies to control SID.

conclusionsSID is a relatively common complication of STN DBS and can be persistent. It often requires specific postoperative management strategies.

Indexed as

Deep Brain StimulationDyskinesiasParkinson DiseaseSubthalamic NucleusAdultAgedFemaleHumansMaleMiddle AgedRetrospective Studiesdeep brain stimulationdyskinesiasParkinson's diseasestimulation‐induced dyskinesias

Identifiers

PMID40249002
PMCPMC12481422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.