Evidence map›Paper›PMID 40248983›Full record

ArticleInternational journal of dermatology2025

Correlating Optical Coherence Tomography and Other Noninvasive Imaging Features With Atrophic and Hypertrophic Skin Photoaging.

Stefania Guida, Silvana Ciardo, Hassan Galadari, Barbara De Pace, Marco Manfredini, Johanna Chester, Shaniko Kaleci, Ilaria Proietti, Carmen Cantisani, Simone Michelini and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Stefania GuidaSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Silvana CiardoDermatology Unit, Department of Surgical, Medical, Dental and Morphological Science With Interest Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Hassan GaladariCollege of Medicine and Health Sciences, United Arab Emirates University, Al Ain, UAE.ORCID https://orcid.org/0000-0001-8223-2769
Barbara De PaceDermatology Unit, Department of Surgical, Medical, Dental and Morphological Science With Interest Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Marco ManfrediniDermatology Unit, Department of Surgical, Medical, Dental and Morphological Science With Interest Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Johanna ChesterDermatology Unit, Department of Surgical, Medical, Dental and Morphological Science With Interest Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Shaniko KaleciDermatology Unit, Department of Surgical, Medical, Dental and Morphological Science With Interest Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Ilaria ProiettiDermatology Unit Daniele Innocenzi, A. Fiorini Hospital, Terracina, Italy.
Carmen CantisaniDermatology Unit, Department of Clinical Internal Anesthesiologic Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.
Simone MicheliniDermatology Unit, Department of Clinical Internal Anesthesiologic Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.
Camilla ChelloDermatology Unit, Department of Clinical Internal Anesthesiologic Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0002-3142-1831
Camila ScharfDermatology Unit, University of Campania L.Vanvitelli, Naples, Italy.ORCID https://orcid.org/0000-0003-3705-7310
Caterina LongoDermatology Unit, Department of Surgical, Medical, Dental and Morphological Science With Interest Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Steven P NisticòDermatology Unit, Department of Clinical Internal Anesthesiologic Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.
Francesca FarnetaniDermatology Unit, Department of Surgical, Medical, Dental and Morphological Science With Interest Transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Franco RongiolettiSchool of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
Giovanni PellacaniDermatology Unit, Department of Clinical Internal Anesthesiologic Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccording to morphological and clinical differences, atrophic (AP) and hypertrophic (HP) skin photoaging types have been reported. The current study examines the correlation between optical coherence tomography (OCT) and dynamic-OCT (D-OCT) features in subjects with skin photoaging types classified as AP, HP, or controls. Furthermore, we aim to define the correlations between OCT/D-OCT and other noninvasive skin imaging features (standardized clinical photography and reflectance confocal microscopy [RCM]).

methodsWe explored the correlations between skin photoaging types, OCT/D-OCT, and noninvasive skin imaging features. A total of 58 patients were clinically classified as AP (n = 17), HP (n = 24), or controls (n = 17).

resultsAP subjects showed higher D-OCT vessel assets and vessel densities (p < 0.05) compared to HP and control subjects. A significant correlation was established between standardized clinical evidence of wrinkles and RCM collagen scores. Dermal variations in HP subjects represent the underlying substrate of wrinkles.

conclusionsDespite the limited cohort, these results contribute to the current knowledge of morphologic differences between AP and HP subjects. Treatment should consider morphologic changes according to skin photoaging phenotypes for optimal personalized medicine.

Indexed as

SkinSkin AgingTomography, Optical CoherenceAdultAgedAtrophyCase-Control StudiesCollagenFemaleHumansHypertrophyMaleMicroscopy, ConfocalMiddle AgedPhotographyCollagenatrophic photoagingcollagenelastosishypertrophic photoagingoptical coherence tomographyphotoagingvesselwrinkles

Identifiers

PMID40248983
PMCPMC12256723

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.