Evidence map›Paper›PMID 40248850›Full record

ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2025

Snakebite cases and treatment outcomes in the Afar region, Ethiopia: a retrospective and prospective study approach.

Abebe M Aga, Demise Mulugeta, Abera Motuma, Bilise Wakitole, Kedir Mohammed, Fanos Tadesse Woldemariyam, Henok Ferede, Zinash Teferi, Shambel Tadesse, Jemal Mohammed and 4 more

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Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Abebe M AgaVaccine, Diagnostics and Medical Device R&D, Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.ORCID 0000-0003-2268-7707
Demise MulugetaVaccine, Diagnostics and Medical Device R&D, Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.
Abera MotumaVaccine, Diagnostics and Medical Device R&D, Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.
Bilise WakitoleVaccine, Diagnostics and Medical Device R&D, Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.
Kedir MohammedAfar Region Health Bureau, P.O. Box 26, Semera, Ethiopia.
Fanos Tadesse WoldemariyamVaccine, Diagnostics and Medical Device R&D, Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.
Henok FeredeVaccine, Diagnostics and Medical Device R&D, Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.
Zinash TeferiVaccine, Diagnostics and Medical Device R&D, Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.
Shambel TadesseVaccine, Diagnostics and Medical Device R&D, Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.
Jemal MohammedVaccine, Diagnostics and Medical Device R&D, Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.
Anberber AlemuVaccine, Diagnostics and Medical Device R&D, Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.
Dejene GetachewVaccine, Diagnostics and Medical Device R&D, Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.
Dassalegn MuletaVaccine, Diagnostics and Medical Device R&D, Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.
Dereje NigussieVaccine, Diagnostics and Medical Device R&D, Armauer Hansen Research Institute, P.O. Box 1005, Addis Ababa, Ethiopia.

Funding

Ministry of Health, EthiopiaWellcome Trust
6 · The paper itself

Abstract

backgroundSnakebite envenomation remains a public health issue, particularly in rural areas. Quick and accurate case identification, coupled with timely treatment, is essential to prevent fatalities and complications.

methodsRetrospective and prospective data consisted of 245 snakebite cases admitted to hospitals in the Afar region, Ethiopia, from September 2023 to July 2024 (retrospective), while prospective data were collected from July to October 2024. The analysis focused on case prevalence, time to treatment, service availability, treatment received, length of hospital stays, recovery times and patient outcomes.

resultsOf 245 cases, 66.1% (n=162) were retrospective and 33.9% (n=83) prospective. Most patients were male (71.6%); the largest age group was 15-29 y (59.6%); most patients required hospital stays of 2-3 d (56.7%). In the majority of cases, recovery took 4-7 d (36.23%). The fatality rate was 3.3%; >46.54% of patients received treatment >7 d after snakebite, mainly because of the long distance traveled to reach healthcare facilities with access to antivenom.

conclusionsIt is essential to strengthen community health units by equipping them with trained personnel and sufficient antivenom supplies to ensure prompt care. Implementing public awareness and promoting local antivenom production could reduce treatment costs and improve patient outcomes.

Indexed as

AntiveninsSnake BitesAdolescentAdultAgedChildChild, PreschoolEthiopiaFemaleHumansLength of StayMaleMiddle AgedProspective StudiesRetrospective StudiesTime-to-TreatmentAntiveninsAfarhealthcarerecovery timesnakebite envenomationtreatment outcomes

Identifiers

PMID40248850
PMCPMC12403212

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.