Evidence map›Paper›PMID 40248715›Full record

ArticleFrontiers in immunology2025

Development of a multi-epitope vaccine from outer membrane proteins and identification of novel drug targets against

Safoura Moradkasani, Saber Esmaeili, Mohammad Reza Asadi Karam, Ehsan Mostafavi, Behzad Shahbazi, Amir Salek Farrokhi, Mohsen Chiani, Farzad Badmasti

Abstract read
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Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  3. Computational design of a novel chimeric multi-epitope vaccine against chlamydia trachomatis serovar a to prevent trachoma.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Safoura MoradkasaniWHO Collaborating Centre for Vector-Borne Diseases, Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, Iran.
Saber EsmaeiliWHO Collaborating Centre for Vector-Borne Diseases, Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, Iran.
Mohammad Reza Asadi KaramDepartment of Molecular Biology, Pasteur Institute of Iran, Tehran, Iran.
Ehsan MostafaviWHO Collaborating Centre for Vector-Borne Diseases, Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, Iran.
Behzad ShahbaziSchool of Pharmacy, Semnan University of Medical Sciences, Semnan, Iran.
Amir Salek FarrokhiDepartment of Immunology, Pasteur Institute of Iran, Tehran, Iran.
Mohsen ChianiDepartment of Nanobiotechnology, Pasteur Institute of Iran, Tehran, Iran.
Farzad BadmastiDepartment of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: This study presents an Results: Of 1,921 proteins, we identified 12 promising protein vaccine candidates from Conclusion: This study designed an MEV and proposed novel drug targets to address tularemia, offering broad protection against various

Indexed as

Bacterial Outer Membrane ProteinsBacterial VaccinesFrancisella tularensisTularemiaAnimalsComputer SimulationEpitopesHumansVaccine DevelopmentBacterial Outer Membrane ProteinsBacterial VaccinesEpitopesdrug targetFrancisella tularensismulti-epitope vaccinereverse vaccinologytularemia

Identifiers

PMID40248715
PMCPMC12003292

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.