Evidence map›Paper›PMID 40248686›Full record

ArticleEssential chem2025

Synthesis of Functionalized Benzocycloheptene Analogs.

Shivangi Kharbanda, Osaid Alkhamayseh, Georgia Eastham, Jimmie D Weaver

Abstract read
In one paragraph

Article in Essential chem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shivangi KharbandaDepartment of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Osaid AlkhamaysehDepartment of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Georgia EasthamDepartment of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States.
Jimmie D WeaverDepartment of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States.

Funding

Contra-Thermodynamic Catalysis and Fluorine Sculpting; Two Counter Cultural Approaches to SynthesisR35GM139613 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI WEAVER, JIMMIE DEAN · 2021 to 2025
$1.9M
NIGMS NIH HHS R35 GM139613
6 · The paper itself

Abstract

The benzocycloheptene core is structurally important motif that appears within a wide array of natural products, and benzocycloheptene has recently been demonstrated to undergo [3+2] photo-sensitized cycloaddition reactions. Thus, there is a need for efficient synthetic protocols to access this motif. Herein, we provide efficient strategies to achieve highly functionalized benzocycloheptene derivatives starting from commercially available 1-benzosuberone and 1-tetralone. We anticipate that these benzocycloheptene compounds will serve as excellent precursors for a diverse array of chemical reactions.

Indexed as

Benzazepinesbenzocycloheptenebenzosuberone derivatizationclick chemistrySchmidt reactiontetralone derivatization

Identifiers

PMID40248686
PMCPMC12002400

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.