ArticleHepatology forum2025
Validation of functional liver imaging scores derived on gadoxetic acid-enhanced MRI in hepatocellular carcinoma patients.
Article in Hepatology forum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Liver Functions in Patients with Chronic Liver Disease and Liver Cirrhosis: Correlation of FLIS and LKER with PALBI Grade and APRI.Current medical imaging · 2025Article
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4 authors.
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Abstract
Background and Aim: To investigate the correlation of the functional liver imaging scores (FLIS) and the scoring system in hepatocellular carcinoma (HCC) patients. Materials and Methods: Between April 2015 and December 2022, the HCC patients who underwent gadoxetic acid-enhanced MRI were analyzed. Three parameters on hepatobiliary phase images were evaluated for FLIS: liver parenchymal enhancement, biliary excretion, and signal intensity of the portal vein. The correlation between Child-Turcotte-Pugh (CTP) classification, the albumin-bilirubin (ALBI) grade, and Fibrosis-4 (F-4) score, and FLIS were analyzed. Receiver operating characteristic curve analysis was performed to demonstrate the cut-off value of FLIS for differentiating between CTP classification and ALBI grade. Results: We retrospectively analyzed 178 HCC patients (144 men, 34 women; mean age, 65.9 years). A moderate negative correlation was present between CTP classification and ALBI grade, and FLIS (r=-0.596 and r=-0.513, respectively). FLIS ≤3 was determined as the most optimal criterion for differentiating CTP A or B patients from CTP C patients. Conclusion: This study showed that the FLIS is a simple, non-invasive imaging marker for the assessment of liver function in HCC patients.
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