Evidence map›Paper›PMID 40248531›Full record

ArticleCureus2025

From Breast to Eye: A Rare Case of Ocular Metastasis From Luminal Breast Cancer in a Nicaraguan Patient.

Gilberto A Altamirano, Christopher Romero, Catherine S Moreno Cabrera, Johanna I Sobalvarro, Lorenzo E Aragón Conrado

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gilberto A AltamiranoGynecologic Oncology, Military Teaching Hospital "Dr. Alejandro Dávila Bolaños", Managua, NIC.
Christopher RomeroSchool of Medicine, Military Teaching Hospital "Dr. Alejandro Dávila Bolaños", Managua, NIC.
Catherine S Moreno CabreraSchool of Medicine, Military Teaching Hospital "Dr. Alejandro Dávila Bolaños", Managua, NIC.
Johanna I SobalvarroGynecologic Oncology, Military Teaching Hospital "Dr. Alejandro Dávila Bolaños", Managua, NIC.
Lorenzo E Aragón ConradoMedical Education, Military Teaching Hospital "Dr. Alejandro Dávila Bolaños", Managua, NIC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ocular metastases from breast cancer are rare but significant, with invasive lobular carcinoma (ILC) showing a higher tendency for ocular involvement than invasive ductal carcinoma (IDC). Radiotherapy is the main treatment, but the prognosis is poor. This case involves a 37-year-old woman with a history of bilateral breast cancer, initially treated with surgery, chemotherapy, and radiotherapy. She later developed pulmonary progression, bone metastases, and other complications. The patient experienced worsening vision loss, headaches, tinnitus, and systemic decline. Imaging showed brain lesions and choroidal metastasis. Extensive metastasis was confirmed, including in the pleura, liver, and bones. Ophthalmologic evaluation revealed increased intraocular pressure, requiring medical management and planned cyclophotocoagulation. Due to the advanced disease, a palliative care approach was initiated, with radiotherapy planned for ocular metastasis. This case highlights the aggressive nature of metastatic luminal B breast cancer with ocular involvement and underscores the importance of early detection and a multidisciplinary approach to patient care.

Indexed as

breast cancerchoroidal metastasisocular metastasisradiotherapysupportive and palliative care

Identifiers

PMID40248531
PMCPMC12004030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.