Evidence map›Paper›PMID 40248507›Full record

ArticleBiofilm2025

A biofilm-targeting lipo-peptoid to treat

Samuel J T Wardell, Deborah B Y Yung, Josefine E Nielsen, Rajesh Lamichhane, Kristian Sørensen, Natalia Molchanova, Claudine Herlan, Jennifer S Lin, Stefan Bräse, Lyn M Wise and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biofilm, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Samuel J T WardellDepartment of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
Deborah B Y YungDepartment of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
Josefine E NielsenDepartment of Bioengineering, Stanford University, School of Medicine, Stanford, CA 94305, USA.
Rajesh LamichhaneDepartment of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
Kristian SørensenDepartment of Bioengineering, Stanford University, School of Medicine, Stanford, CA 94305, USA.
Natalia MolchanovaThe Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
Claudine HerlanInstitute of Biological and Chemical Systems - Functional Molecular Systems (IBCS-FMS), Karlsruhe Institute of Technology (KIT), Germany.
Jennifer S LinDepartment of Bioengineering, Stanford University, School of Medicine, Stanford, CA 94305, USA.
Stefan BräseInstitute of Biological and Chemical Systems - Functional Molecular Systems (IBCS-FMS), Karlsruhe Institute of Technology (KIT), Germany.
Lyn M WiseMaurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, 1042, New Zealand.
Annelise E BarronDepartment of Bioengineering, Stanford University, School of Medicine, Stanford, CA 94305, USA.
Daniel PletzerDepartment of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic-resistant bacterial infections are a significant clinical challenge, especially when involving multiple species. Antimicrobial peptides and their synthetic analogues, peptoids, which target bacterial cell membranes as well as intracellular components, offer potential solutions. We evaluated the biological activities of novel peptoids TM11-TM20, which include an additional charged

Indexed as

Abscess modelBiofilmsHost-mimicking conditionsPeptidesPeptoidsPolymicrobial

Identifiers

PMID40248507
PMCPMC12005307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.