Evidence map›Paper›PMID 40248261›Full record

ArticleJCEM case reports2025

Hypertension and Carcinoid Heart Disease as Initial Manifestations of Ovarian Carcinoid Tumor.

Andreia Martins Fernandes, Sara Reis, Catarina Neves, David Prieto, Paulo Aldinhas, Raquel G Martins

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JCEM case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andreia Martins FernandesDepartment of Endocrinology, Instituto Português de Oncologia de Coimbra Francisco Gentil, E.P.E., Coimbra 3000-075, Portugal.ORCID https://orcid.org/0000-0003-2158-4714
Sara ReisDepartment of Pathology, Instituto Português de Oncologia de Coimbra Francisco Gentil, E.P.E., Coimbra 3000-075, Portugal.
Catarina NevesDepartment of Cardiology, Instituto Português de Oncologia de Coimbra Francisco Gentil, E.P.E., Coimbra 3000-075, Portugal.
David PrietoCardiothoracic Surgery Center, Centro Hospitalar e Universitário de Coimbra, E.P.E., Coimbra 3000-075, Portugal.
Paulo AldinhasDepartment of Ginecology, Instituto Português de Oncologia de Coimbra Francisco Gentil, E.P.E., Coimbra 3000-075, Portugal.
Raquel G MartinsDepartment of Endocrinology, Instituto Português de Oncologia de Coimbra Francisco Gentil, E.P.E., Coimbra 3000-075, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian carcinoid tumors (OCTs) are rare and may cause carcinoid syndrome (CS) even in the absence of liver metastases. Carcinoid heart disease (CHD), which develops in up to 50% of patients with CS, substantially affects morbidity and mortality. While prognosis is generally favorable, maintaining clinical suspicion and early diagnosis is crucial to prevent the development of advanced heart failure or metastases. We present a case of a woman exhibiting asthenia, diarrhea, and de novo severe hypertension. Echocardiography revealed typical features of CHD. Elevated urinary levels of 5-hydroxyindoleacetic acid (5-HIAA) corroborated the diagnosis of CS.

Indexed as

carcinoid heart diseasecarcinoid syndromecarcinoid tumorhypertensionneuroendocrine tumorsovarian neoplasms

Identifiers

PMID40248261
PMCPMC12003261

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.