Evidence map›Paper›PMID 40248216›Full record

ArticlePulmonary circulation2025

Alterations in ECG and Right Heart Catheterization Data in PAH Patients Who Died From Sudden Death Compared With Right Heart Failure.

Alexandra B Flemington, Jeffery Annis, Evan L Brittain, Anna R Hemnes

Abstract readLetter
In one paragraph

Article in Pulmonary circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexandra B FlemingtonDepartment of Medicine Vanderbilt University Medical Center Nashville Tennessee USA.ORCID 0009-0004-3237-5525
Jeffery AnnisDepartment of Cardiology Vanderbilt Institute for Clinical and Translational Research Nashville Tennessee USA.
Evan L BrittainDepartment of Cardiology Vanderbilt Institute for Clinical and Translational Research Nashville Tennessee USA.
Anna R HemnesDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine Vanderbilt University Medical Center Nashville Tennessee USA.ORCID 0000-0002-2755-5845

Funding

Network Medicine and Systems Pharmacology to Advance Precision Medicine in Combined Pulmonary HypertensionR01HL163960 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Evan L Brittain, Anna R Hemnes · 2022 to 2026
$3.4M
Mentorship in Pulmonary Vascular DiseaseK24HL155891 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Anna R Hemnes · 2022 to 2026
$573k
NHLBI NIH HHS K24 HL155891NHLBI NIH HHS R01 HL163960
6 · The paper itself

Abstract

A meaningful number of patients with PAH die suddenly, and there is little data to understand the events surrounding sudden death in PAH. We tested the hypothesis that sudden death is associated with pre-mortem ECG or hemodynamics changes compared to those who died of RHF. We extracted data from the Vanderbilt University Medical Center Synthetic Derivative. Patients 18 years of age and older with Group 1 PAH secondary to any etiology who died between 2009 and 2017 with both ECG and RHC data from the inpatient and outpatient setting were included in the study. Continuous variables were compared using the Wilcoxon rank-sum test while categorical variables were compared using the

Identifiers

PMID40248216
PMCPMC12005591

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.