Evidence map›Paper›PMID 40248186›Full record

ArticleMicrofluidics and nanofluidics2025

Modelling, simulation, and experimental characterization of particle sedimentation inside a horizontal syringe.

Maryamsadat Ghoreishi, Efsun Senturk, Gianluca Cidonio, Chiara Scognamiglio, Zita Salajková, Mara Riminucci, Alessandro Corsi, Giancarlo Ruocco, Marco Leonetti, Riccardo Reale

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In one paragraph

Article in Microfluidics and nanofluidics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maryamsadat GhoreishiCenter for Life Nano- and Neuro- Sciences, Italian Institute of Technology, Rome, Italy.ORCID 0000-0002-1923-1488
Efsun SenturkCenter for Life Nano- and Neuro- Sciences, Italian Institute of Technology, Rome, Italy.
Gianluca CidonioCenter for Life Nano- and Neuro- Sciences, Italian Institute of Technology, Rome, Italy.ORCID 0000-0002-9445-6994
Chiara ScognamiglioCenter for Life Nano- and Neuro- Sciences, Italian Institute of Technology, Rome, Italy.ORCID 0000-0001-9616-4277
Zita SalajkováCenter for Life Nano- and Neuro- Sciences, Italian Institute of Technology, Rome, Italy.ORCID 0000-0001-5085-9698
Mara RiminucciDepartment of Mechanical and Aerospace Engineering, Sapienza University of Rome, via Eudossiana 18, 00184 Rome, Italy.ORCID 0000-0002-8643-9211
Alessandro CorsiDepartment of Mechanical and Aerospace Engineering, Sapienza University of Rome, via Eudossiana 18, 00184 Rome, Italy.ORCID 0000-0001-6896-4509
Giancarlo RuoccoCenter for Life Nano- and Neuro- Sciences, Italian Institute of Technology, Rome, Italy.ORCID 0000-0002-2762-9533
Marco LeonettiCenter for Life Nano- and Neuro- Sciences, Italian Institute of Technology, Rome, Italy.ORCID 0000-0001-7106-0850
Riccardo RealeCenter for Life Nano- and Neuro- Sciences, Italian Institute of Technology, Rome, Italy.ORCID 0000-0002-7697-8895

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sedimentation is the settling of solid particles in a liquid medium driven by gravity. This phenomenon poses significant challenges in experimental lab-on-chip (LOC) applications, as they often involve a biological sample to be loaded inside a syringe for prolonged periods (e.g. 3D bioprinting, microfluidic cytometers). Mitigating solutions such as mechanical agitators or buffer adjustments exist, but increase the complexity and cost of the setup. In this work, we developed a model of particle sedimentation inside a horizontal syringe, which highlights the importance of several parameters: syringe radius, particle terminal velocity in the buffer, syringe outlet position, and flow-rate. The model provides a simple way to estimate the concentration half-life ( Supplementary Information: The online version contains supplementary material available at 10.1007/s10404-025-02802-x.

Indexed as

3D bioprintingBioengineeringConcentration half-lifeLab-on-a-chipSedimentationSyringe

Identifiers

PMID40248186
PMCPMC12000163

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.