Evidence map›Paper›PMID 40248182›Full record

ArticleBeyoglu eye journal2025

Pulsating Enophthalmos as an Initial Symptom of Neurofibromatosis Type 1.

Aslihan Yilmaz Cebi, Bilge Batu Oto, Oguzhan Kilicarslan, Ahmet Murat Sarici

Abstract readCase Reports
In one paragraph

Article in Beyoglu eye journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aslihan Yilmaz CebiDepartment of Ophthalmology, Cerkezkoy State Hospital, Tekirdag, Türkiye.
Bilge Batu OtoDepartment of Ophthalmology, Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Türkiye.
Oguzhan KilicarslanDepartment of Ophthalmology, Ayancik State Hospital, Sinop, Türkiye.
Ahmet Murat SariciDepartment of Ophthalmology, Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a neurofibromatosis type 1 (NF-1) patient with pulsating enophthalmos as the first symptom. A 25-year-old female presented to us with posterior displacement of the left eye and a headache. The patient had enophthalmos with pulsations. A slit lamp examination revealed bilateral Lisch nodules and a computed tomography scan of the orbit demonstrated aplasia of the greater wing of the sphenoid bone on the left. The patient had café-au-lait macules, a history of scoliosis, and splenectomy operations. Genetic counseling confirmed the diagnosis of NF-1. NF-1 is a multisystemic, autosomal dominant genetic disease with cutaneous, neurologic, cardiovascular, and ophthalmologic manifestations. Dysfunction of tumor suppressor gene NF-1 is the main cause. Therefore, periodic screening for tumor development is required. Since NF-1 has several neuro-ophthalmological findings, ophthalmologists can play a significant role in its diagnosis and management.

Indexed as

EnophthalmosNeurofibromatosis type 1PhakomatosesSphenoid boneTumor supressor gene

Identifiers

PMID40248182
PMCPMC12000901

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.