Evidence map›Paper›PMID 40248168›Full record

ArticleIntegrative and complementary therapies2024

Efficacy of Home-Based Remotely Supervised Transcranial Direct Current Stimulation for Managing Neuropsychiatric Symptoms in Older Adults With Alzheimer's Disease and Related Dementias.

Juyoung Park, Chiyoung Lee, Lifeng Lin, James Galvin, Mindy J Fain, Angela Allen, Lindsey Park, Hyochol Ahn

Abstract read
In one paragraph

Article in Integrative and complementary therapies, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Juyoung ParkBrain Digital Technology Laboratory, University of Arizona College of Nursing, Tucson, Arizona, USA.
Chiyoung LeeUniversity of Arizona College of Nursing, Tucson, Arizona, USA.
Lifeng LinEpidemiology and Biostatics Department, University of Arizona College of Public Health, Tucson, Arizona, USA.
James GalvinDepartment of Neurology Comprehensive Center for Brain Health, University of Miami Miller School of Medicine, Boca Raton, Florida, USA.
Mindy J FainDivision of General Internal Medicine, Geriatrics and Palliative Medicine, and the University of Arizona Center on Aging, University of Arizona College of Medicine, Tucson, Arizona, USA.
Angela AllenBanner-University Medical Center, Phoenix, Arizona, USA.
Lindsey ParkUniversity of Arizona College of Nursing, Tucson, Arizona, USA.
Hyochol AhnUniversity of Arizona College of Nursing, Tucson, Arizona, USA.

Funding

Pain-related Brain Mechanisms for Pain Catastrophizing Behavior in Response to Home-based Mindfulness-based Meditation Paired with Transcranial Direct Current StimulationR01NR019051 · NINR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI AHN, HYOCHOL · 2020 to 2025
$2.9M
Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults with Knee Osteoarthritis: A Phase II Randomized Sham-Controlled TrialR15NR018050 · NINR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MATHIS, KENNETH B · 2019 to 2020
$618k
NINR NIH HHS R01 NR019051NINR NIH HHS R15 NR018050
6 · The paper itself

Abstract

Background: Neuropsychiatric symptoms (NPS) are prevalent among persons with Alzheimer's disease and related dementias (ADRD). However, there are limited safe and effective nonpharmacological treatments for controlling NPS. Transcranial direct current stimulation (tDCS) is a promising noninvasive and safe treatment. Materials and Methods: This study investigated the effects of remotely supervised tDCS in managing NPS in older adults with mild to moderate ADRD. Forty older adults diagnosed with early-stage ADRD were randomly assigned in a 1:1 ratio to receive home-based active tDCS ( Results: Results showed a significantly greater improvement in the following NPS: scratching ( Conclusion: This study shows promising initial results for using home-based, remotely supervised tDCS to manage NPS, such as nighttime behaviors, changes in eating and appetite, and scratching. Larger studies with more participants are needed to explore various tDCS doses and their long-term effects on NPS.

Indexed as

neuropsychiatric symptomsolder adultstranscranial direct current stimulation

Identifiers

PMID40248168
PMCPMC12005119

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.