Evidence map›Paper›PMID 40248129›Full record

ArticleHemaSphere2025

Spironolactone inhibits the NLRP1 inflammasome and alleviates defective erythropoiesis in Diamond-Blackfan anemia.

Lola Rodríguez-Ruiz, Juan M Lozano-Gil, María Ocaña-Esparza, Ana M Conesa-Hernández, Ana B Pérez-Oliva, José L Fuster, Andrés Jérez, Laura Murillo-Sanjuán, Cristina Díaz-de-Heredia, Guzmán López-de-Hontanar and 6 more

Abstract readLetter
In one paragraph

Article in HemaSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Lola Rodríguez-RuizDepartmento de Biología Celular e Histología Facultad de Biología, Universidad de Murcia Murcia Spain.
Juan M Lozano-GilDepartmento de Biología Celular e Histología Facultad de Biología, Universidad de Murcia Murcia Spain.
María Ocaña-EsparzaDepartmento de Biología Celular e Histología Facultad de Biología, Universidad de Murcia Murcia Spain.
Ana M Conesa-HernándezDepartmento de Biología Celular e Histología Facultad de Biología, Universidad de Murcia Murcia Spain.
Ana B Pérez-OlivaInstituto Murciano de Investigación Biosanitaria (IMIB)-Pascual Parrilla Murcia Spain.
José L FusterInstituto Murciano de Investigación Biosanitaria (IMIB)-Pascual Parrilla Murcia Spain.
Andrés JérezInstituto Murciano de Investigación Biosanitaria (IMIB)-Pascual Parrilla Murcia Spain.
Laura Murillo-SanjuánCentro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III Madrid Spain.
Cristina Díaz-de-HerediaCentro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III Madrid Spain.
Guzmán López-de-HontanarCentro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III Madrid Spain.
Julián SevillaCentro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III Madrid Spain.
Diana García-MorenoInstituto Murciano de Investigación Biosanitaria (IMIB)-Pascual Parrilla Murcia Spain.
María L CayuelaInstituto Murciano de Investigación Biosanitaria (IMIB)-Pascual Parrilla Murcia Spain.
Alicia Martínez-LópezInstituto Murciano de Investigación Biosanitaria (IMIB)-Pascual Parrilla Murcia Spain.
Sylwia D TyrkalskaInstituto Murciano de Investigación Biosanitaria (IMIB)-Pascual Parrilla Murcia Spain.
Victoriano MuleroDepartmento de Biología Celular e Histología Facultad de Biología, Universidad de Murcia Murcia Spain.ORCID 0000-0001-9527-0211

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40248129
PMCPMC12005213

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.