Evidence map›Paper›PMID 40248108›Full record

ArticleKDD : proceedings. International Conference on Knowledge Discovery & Data Mining2025

A Deep Subgrouping Framework for Precision Drug Repurposing via Emulating Clinical Trials on Real-world Patient Data.

Seungyeon Lee, Ruoqi Liu, Feixiong Cheng, Ping Zhang

Abstract read
In one paragraph

Article in KDD : proceedings. International Conference on Knowledge Discovery & Data Mining, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. When evidence meets artificial intelligence.Lancet regional health. Americas · 2026
    Review
  3. Article
  4. REACT (Real-world Emulated Clinical Trials): A Framework for Drug Repurposing Applied to Osteoporotic Fractures.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Seungyeon LeeThe Ohio State University Ohio, USA.
Ruoqi LiuThe Ohio State University Ohio, USA.
Feixiong ChengCleveland Clinic Ohio, USA.
Ping ZhangThe Ohio State University Ohio, USA.

Funding

A Statistical Network Pharmacology Approach for Early Detection of Adverse Drug EventsR01GM141279 · NIGMS · OHIO STATE UNIVERSITY · PI ZHANG, PENGYUE, ZHANG, PING · 2021 to 2023
$937k
NIGMS NIH HHS R01 GM141279
6 · The paper itself

Abstract

Drug repurposing identifies new therapeutic uses for existing drugs, reducing the time and costs compared to traditional

Indexed as

Alzheimer’s DiseaseDrug RepurposingElectronic Health RecordReal-World DataSubgroup AnalysisTreatment Effect Estimation

Identifiers

PMID40248108
PMCPMC12001032

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.