ArticleFrontiers in medicine2025
Effect of different prophylactical doses of ondansetron for the hemodynamic stability in patients undergoing cesarean section: a randomized controlled study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05475873 (Ondansetron for Postspinal Anesthesia Hypotension in Patients Undergoing Cesarean Section), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ondansetron for Postspinal Anesthesia Hypotension in Patients Undergoing Cesarean Section: A Randomized, Controlled Trial
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Major Adverse Cardiac Events with Ondansetron: A Systematic Review.Clinical pharmacology and therapeutics · 2026Pooled it
- Severe Post-spinal Bezold-Jarisch Reflex During Emergency Caesarean Delivery Unmasking Wolff-Parkinson-White Pattern.Cureus · 2026Article
- Diagnostic accuracy of the HUAWEI WATCH D for measuring spinal anesthesia-induced hypotension during elective cesarean section: a diagnostic test.Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: 5-hydroxytryptamine 3 (5-HT3) receptor antagonists have been reported to reduce post-spinal anesthesia hypotension, though their efficacy remains controversial. We investigated the effect of prophylactic ondansetron on hemodynamic stability in patients undergoing cesarean section following spinal anesthesia. Methods: Patients scheduled for elective cesarean section ( Results: The primary outcomes (median performance error, MDPE and median absolute performance error, MDAPE) were significantly different among the three groups. ( Conclusion: Prophylactic 4 mg or 8 mg ondansetron improved hemodynamic stability after spinal anesthesia in cesarean section; however, only 8 mg reduced post-spinal anesthesia hypotension. Clinical trial registration: Clinicaltrials.gov, NCT05475873.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.