Evidence map›Paper›PMID 40248022›Full record

ArticleFrontiers in pediatrics2025

Early successful weaning from continuous positive airway pressure in infants <32 weeks of gestation: predictors of success.

Lisa Marie Bünte, Christina Walden, Jennifer Schlecht, Benedikt Bubl, Mircea-Horia Popa-Todirenchi, Susanne Tippmann, Julia Winter, Eva Mildenberger, André Kidszun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lisa Marie BünteDivision of Neonatology, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Christina WaldenDivision of Neonatology, Center for Pediatric and Adolescent Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Jennifer SchlechtDivision of Pediatric Epidemiology, Institute for Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Benedikt BublDivision of Neonatology, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Mircea-Horia Popa-TodirenchiDivision of Neonatology, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Susanne TippmannDivision of Neonatology, Center for Pediatric and Adolescent Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Julia WinterDivision of Neonatology, Center for Pediatric and Adolescent Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Eva Mildenberger *Division of Neonatology, Center for Pediatric and Adolescent Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
André Kidszun *Division of Neonatology, Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To identify demographic and clinical variables predictive of early successful weaning in preterm infants weaned off continuous positive airway pressure (CPAP). Methods: Single-center retrospective analysis of preterm infants < 32 0/7 weeks gestational age (GA) weaned off CPAP according to a standardized protocol April 2013-March 2017. Infants were categorized into (1) early successfully weaned (Early-W) if weaned at the first attempt and (2) delayed weaned (Delayed-W) if more than one attempt was necessary. Potential predictor variables were predefined. Association with Early-W was analyzed by multivariable logistic regression with model selection using the Akaike information criterion (AIC). Model performance was evaluated using the area under the receiver operating characteristic (ROC-AUC). Results: 145 infants [79 (54.5%) were Early-W and 66 (45.5%) Delayed-W] with complete data sets were included in the analysis. A model of higher GA [odds ratio (OR) 1.66; 95% confidence interval (CI) 1.39, 2.03; Conclusion: This study identified GA, PDA and median RR to predict early successful weaning in preterm infants weaned off CPAP. The predictive value of median RR in the 12 h prior to CPAP cessation is considered a novelty requiring further prospective investigation, with RR being a clinical parameter commonly employed in routine practice and practical for everyday application.

Indexed as

continuous positive airway pressurepredictionpreterm infantrespiratory distressrespiratory rateweaning

Identifiers

PMID40248022
PMCPMC12003399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.