Evidence map›Paper›PMID 40247320›Full record

ReviewJournal of nanobiotechnology2025

The develop of persistent luminescence nanoparticles with excellent performances in cancer targeted bioimaging and killing: a review.

Rongshuang Tan, Jianing Wu, Chunya Wang, Zhengyan Zhao, Xiaoyuan Zhang, Chang Zhong, Zihui Tang, Rui Zheng, Binhong Du, Yunhan He and 2 more

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rongshuang Tan *School and Hospital of Stomatology, Key Laboratory of Dental Maxillofacial Reconstruction & Biological Intelligence Manufacturing of Gansu Province, Lanzhou University, Lanzhou, 730000, People's Republic of China.
Jianing Wu *School and Hospital of Stomatology, Key Laboratory of Dental Maxillofacial Reconstruction & Biological Intelligence Manufacturing of Gansu Province, Lanzhou University, Lanzhou, 730000, People's Republic of China.
Chunya WangSchool and Hospital of Stomatology, Key Laboratory of Dental Maxillofacial Reconstruction & Biological Intelligence Manufacturing of Gansu Province, Lanzhou University, Lanzhou, 730000, People's Republic of China.
Zhengyan ZhaoSchool and Hospital of Stomatology, Key Laboratory of Dental Maxillofacial Reconstruction & Biological Intelligence Manufacturing of Gansu Province, Lanzhou University, Lanzhou, 730000, People's Republic of China.
Xiaoyuan ZhangSchool and Hospital of Stomatology, Key Laboratory of Dental Maxillofacial Reconstruction & Biological Intelligence Manufacturing of Gansu Province, Lanzhou University, Lanzhou, 730000, People's Republic of China.
Chang ZhongSchool and Hospital of Stomatology, Key Laboratory of Dental Maxillofacial Reconstruction & Biological Intelligence Manufacturing of Gansu Province, Lanzhou University, Lanzhou, 730000, People's Republic of China.
Zihui TangSchool and Hospital of Stomatology, Key Laboratory of Dental Maxillofacial Reconstruction & Biological Intelligence Manufacturing of Gansu Province, Lanzhou University, Lanzhou, 730000, People's Republic of China.
Rui ZhengSchool and Hospital of Stomatology, Key Laboratory of Dental Maxillofacial Reconstruction & Biological Intelligence Manufacturing of Gansu Province, Lanzhou University, Lanzhou, 730000, People's Republic of China.
Binhong DuSchool of Physical Science and Technology, Lanzhou University, Lanzhou, 730000, People's Republic of China.
Yunhan HeSchool and Hospital of Stomatology, Key Laboratory of Dental Maxillofacial Reconstruction & Biological Intelligence Manufacturing of Gansu Province, Lanzhou University, Lanzhou, 730000, People's Republic of China.
Yuhua SunSchool of Stomatology, Xuzhou Medical University, Xuzhou, 221000, People's Republic of China. yuhua-sun@xzhmu.edu.cn.
Ping ZhouSchool and Hospital of Stomatology, Key Laboratory of Dental Maxillofacial Reconstruction & Biological Intelligence Manufacturing of Gansu Province, Lanzhou University, Lanzhou, 730000, People's Republic of China. zhoup@lzu.edu.cn.

Funding

CSA West China Clinical Research Fund CSA-W2024-11Fundamental Research Funds for the Central Universities lzujbky-2021-ey14Gansu Province Health Industry Research Project GSWSKY2023-70Joint Research Fund of Gansu Province 24JRRA945Natural Science Foundation of Gansu Province 22YF7FA017
6 · The paper itself

Abstract

The use of fluorescent nanomaterials in tumor imaging and treatment effectively avoids the original limitations of traditional tumor clinical diagnostic methods. The PLNPs emitted persistent luminescence after the end of excitation light. Owing to their superior optical properties, such as a reduced laser irradiation dose, spontaneous fluorescence interference elimination, and near-infrared imaging, PLNPs show great promise in tumor imaging. Moreover, they also achieve excellent anti-tumor therapeutic effects through surface modification and drug delivery. However, their relatively large size and limited surface modification capacity limit their ability to kill tumors effectively enough for clinical applications. Thus, this article reviews the synthesis and modification of PLNPs and the research progress in targeted tumor imaging and tumor killing. We also discuss the challenges and prospects of their future applications in these fields. This review has value for accelerating the design of PLNPs based platform for cancer diagnosis and treatment.

Indexed as

NanoparticlesNeoplasmsAnimalsAntineoplastic AgentsDrug Delivery SystemsHumansLuminescenceOptical ImagingAntineoplastic AgentsBioimagingCancer treatmentCell killingPersistent luminescence nanoparticlesTumor monitoring

Identifiers

PMID40247320
PMCPMC12007383

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.