Evidence map›Paper›PMID 40247297›Full record

ArticleJournal of nanobiotechnology2025

Lactobacillus acidophilus extracellular vesicles-coated UiO-66-NH

Chenyang Cui, Jiaze Tang, Jie Chen, Beining Zhang, Ruonan Li, Qiang Zhang, Chunjing Qiu, Rongchen Chen, Geng Min, Zhaowei Sun and 1 more

Erratum issuedAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Chenyang CuiSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China.ORCID http://orcid.org/0000-0002-3630-1361
Jiaze TangSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China.
Jie ChenSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China.
Beining ZhangSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China.
Ruonan LiSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China.
Qiang ZhangDepartment of Critical Care Medicine, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, China.
Chunjing QiuHenan Key Laboratory of Helicobacter Pylori & Microbiota and Gastrointestinal Cancer, Marshall Medical Research Center, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, China.
Rongchen ChenSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China.
Geng MinSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China.
Zhaowei SunSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China. szw@zzu.edu.cn.
Haibo WengSchool of Life Sciences, Zhengzhou University, Zhengzhou, Henan, 450001, China. whb@zzu.edu.cn.

Funding

Key Research and Development Special Fund of Henan Province 231111311800National Natural Science Foundation of China 82402437
6 · The paper itself

Abstract

Ulcerative colitis (UC) is a complex and chronic inflammatory bowel disease whose pathogenesis involves genetic and environmental factors, which poses a challenge for treatment. Here, we have designed an innovative integrated therapeutic strategy using Lactobacillus acidophilus extracellular vesicles (EVs) to encapsulate UiO-66-NH

Indexed as

Colitis, UlcerativeExtracellular VesiclesGastrointestinal MicrobiomeGenetic TherapyLactobacillus acidophilusNanoparticlesRNA, Small InterferingAnimalsHumansMaleMiceMice, Inbred C57BLTumor Necrosis Factor-alphaRNA, Small InterferingTumor Necrosis Factor-alphaLactobacillus acidophilus EVsTargeted gene therapyTNF-α SiRNAUiO-66-NH2Ulcerative colitis

Identifiers

PMID40247297
PMCPMC12007195

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.