Evidence map›Paper›PMID 40247240›Full record

ArticleBMC cancer2025

Prevalence of medical writing in hematological malignancy review articles.

Héctor A Vaquera-Alfaro, Elham Nasrollahi, Yashvin Onkarappa Mangala, David Russler-Germain, Aaron Goodman, Ghulam Rehman Mohyuddin

Abstract read
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Héctor A Vaquera-AlfaroServicio de Hematología, Hospital Universitario "Dr. José Eleuterio González" UANL, Monterrey, Nuevo León, México.ORCID http://orcid.org/0000-0001-9657-9130
Elham NasrollahiDepartment of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Yashvin Onkarappa MangalaHematology/Medical Oncology, Presbyterian Healthcare Services, Albuquerque, NM, USA.
David Russler-GermainDivision of Oncology, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0003-1009-2247
Aaron GoodmanDivision of Blood and Marrow Transplantation, University of California San Diego, San Diego, CA, USA.
Ghulam Rehman MohyuddinDivision of Hematology and Hematological Malignancies, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA. g.mohyuddin@hci.utah.edu.ORCID http://orcid.org/0000-0001-6464-783X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedical writing services, initially developed to streamline manuscript preparation, have raised ethical concerns due to their association with industry influence and spin. While prevalent in oncology and malignant hematology clinical trials, medical writing involvement in review articles remains underexplored, particularly in the hematology literature. Furthermore, conflict of interests of the writers may also affect the content of review articles. This study investigates the prevalence, characteristics, and funding sources of medical writing in malignant hematology review articles and their relationship with the financial conflicts of interest (CoI) among authors.

methodsWe conducted a cross-sectional analysis of review articles published in the five-year period between January 2019 and December 2023 in the ten highest-rated hematology journals (by 2023 Journal Citation Report Impact Factor). Inclusion criteria encompassed narrative and systematic reviews, guidelines, and clinical advice articles, excluding studies focused solely on benign hematology or basic science.

resultsAmong 663 included reviews, medical writing involvement was disclosed in 5.7% of articles in which in no instance the medical writer was included as a co-author; with as high as 21% of review articles in a single journal having disclosed medical writing assistance. Medical writers were primarily industry-sponsored (89%). Reviews on plasma cell malignancies had the highest medical writing usage (11%). Direct CoIs were identified in 28% and 34% of first and last authors, respectively, rising to 71% in drug-specific reviews. Only one journal had explicit policies regulating medical writing in reviews.

conclusionsAlthough the prevalence of medical writing in malignant hematology review articles remains low, at least one journal had over 20% of review articles disclosing medical writer usage. Review articles about specific drugs are often written by authors with direct payments from the manufacturer of the drug in question.

Indexed as

Hematologic NeoplasmsMedical WritingAuthorshipConflict of InterestCross-Sectional StudiesHumansPeriodicals as TopicPrevalenceMalignant hematologyMedical writingReviews

Identifiers

PMID40247240
PMCPMC12007303

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.