Evidence map›Paper›PMID 40247092›Full record

ArticleScientific reports2025

Clinical evaluation of blood flow in femoral head necrosis using color doppler ultrasound.

Tong-Jie Yang, Yan Li, Peng-Peng Wen, Zi-Xuan Wu, Xin Ye, Cheng Zhang, Shi-Yi Sun, Guang-Yi Zhang, Yi-Fei Sun, Cheng-Kun Zhou and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tong-Jie YangWangjing Hospital, China Academy of Chinese Medical Sciences, 6 South Middle Ring Road, Chaoyang District, Beijing, 100102, China.
Yan LiWangjing Hospital, China Academy of Chinese Medical Sciences, 6 South Middle Ring Road, Chaoyang District, Beijing, 100102, China.
Peng-Peng WenFirst Affiliated Hospital of Wenzhou Medical University, No. 2 Fuxue Lane, Ouhai District, Wenzhou, 325000, Zhejiang Province, China.
Zi-Xuan WuWangjing Hospital, China Academy of Chinese Medical Sciences, 6 South Middle Ring Road, Chaoyang District, Beijing, 100102, China.
Xin YeThe Third Affiliated Hospital of Zhejiang, Chinese Medical University, No. 219 Moganshan Road, Xihu District, Hangzhou, 310009, Zhejiang, China.
Cheng ZhangWangjing Hospital, China Academy of Chinese Medical Sciences, 6 South Middle Ring Road, Chaoyang District, Beijing, 100102, China.
Shi-Yi SunWangjing Hospital, China Academy of Chinese Medical Sciences, 6 South Middle Ring Road, Chaoyang District, Beijing, 100102, China.
Guang-Yi ZhangWangjing Hospital, China Academy of Chinese Medical Sciences, 6 South Middle Ring Road, Chaoyang District, Beijing, 100102, China.
Yi-Fei SunWangjing Hospital, China Academy of Chinese Medical Sciences, 6 South Middle Ring Road, Chaoyang District, Beijing, 100102, China.
Cheng-Kun ZhouWangjing Hospital, China Academy of Chinese Medical Sciences, 6 South Middle Ring Road, Chaoyang District, Beijing, 100102, China.
Ren YeFirst Affiliated Hospital of Wenzhou Medical University, No. 2 Fuxue Lane, Ouhai District, Wenzhou, 325000, Zhejiang Province, China.
Hai-Jun HeWangjing Hospital, China Academy of Chinese Medical Sciences, 6 South Middle Ring Road, Chaoyang District, Beijing, 100102, China. drhjhe@126.com.

Funding

Beijing Natural Science Foundation 7222298
6 · The paper itself

Abstract

This study aims to utilize Color Doppler Ultrasound to collect blood flow parameters of the medial circumflex femoral artery and explore the changes in blood flow in osteonecrosis of the femoral head, providing objective indicators for clinical assessment and prognosis. Color Doppler Ultrasound was used to examine the medial circumflex femoral artery in 30 patients with osteonecrosis of the femoral head (52 hips: ARCO Stage I-2 hips, Stage II-24 hips, Stage III-24 hips, Stage IV-2 hips) and 30 healthy controls (57 hips). Arterial diameter and blood flow parameters [peak systolic velocity, resistance index, pulsatility index] were collected and analyzed for vascular and blood flow characteristics in osteonecrosis of the femoral head. (1) Compared with the healthy group, the osteonecrosis group showed significantly lower peak systolic velocity and resistance index, while no significant differences were observed in arterial diameter and pulsatility index. (2) Arterial diameter in Stage I was significantly larger than in Stages II, III, and IV, with no significant differences observed among Stages II, III, and IV. Peak systolic velocity, resistance index, and pulsatility index all significantly decreased with disease progression from Stage I to Stage IV, but no significant difference in pulsatility index was found between Stages II and III. (3) There was no significant difference in arterial diameter between the non-collapsed and collapsed groups; however, peak systolic velocity, resistance index, and pulsatility index were all significantly lower in the collapsed group compared to the non-collapsed group. (1) The alterations in blood supply in femoral head necrosis primarily manifest as changes in blood flow parameters. (2) Vascular morphology and blood flow parameters could potentially be useful indicators for assessing the progression of femoral head necrosis. (3) Changes in blood flow parameters may provide valuable insights into the risk of femoral head collapse.

Indexed as

Femoral ArteryFemur Head NecrosisUltrasonography, Doppler, ColorAdultAgedBlood Flow VelocityCase-Control StudiesFemaleFemur HeadHumansMaleMiddle AgedRegional Blood FlowBlood flow parametersColor doppler ultrasoundMedial circumflex femoral arteryOsteonecrosis of the femoral head

Identifiers

PMID40247092
PMCPMC12006462

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.