Evidence map›Paper›PMID 40247039›Full record

ArticleActa pharmacologica Sinica2025

Complexin 2 contributes to the protective effect of NAD

Xiao-Wen Xu, Xiu-Wen Zhou, Li Zhang, Qing Wang, Xin-Xin Wang, Yi-Ming Jin, Li-Li Li, Mei-Fang Jin, Hai-Ying Wu, Xin Ding and 1 more

Abstract read
In one paragraph

Article in Acta pharmacologica Sinica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiao-Wen Xu *Department of Brain Science, Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215025, China.
Xiu-Wen Zhou *Department of Brain Science, Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215025, China.
Li Zhang *Department of Brain Science, Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215025, China.
Qing WangDepartment of Brain Science, Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215025, China.
Xin-Xin WangDepartment of Brain Science, Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215025, China.
Yi-Ming JinDepartment of Brain Science, Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215025, China.
Li-Li LiDepartment of Brain Science, Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215025, China.
Mei-Fang JinDepartment of Brain Science, Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215025, China.
Hai-Ying WuDepartment of Endocrinology, Genetics and Metabolism, Children's Hospital of Soochow University, Suzhou, 215025, China. hainewhy@126.com.
Xin DingSoochow Key Laboratory of Prevention and Treatment of Child Brain Injury, Children's Hospital of Soochow University, Suzhou, 215025, China. dingxin@suda.edu.cn.
Hong NiDepartment of Brain Science, Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215025, China. nhdoctor@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotinamide adenine dinucleotide (NAD) is a key coenzyme involved in cell metabolism associated with aging, cancer, neurodegenerative diseases and metabolic disorders. We recently showed that NAD

Indexed as

Hypoxia-Ischemia, BrainNADNeuronsNeuroprotective AgentsAnimalsAnimals, NewbornCell SurvivalMaleMiceMice, Inbred C57BLMice, KnockoutNADNeuroprotective AgentsCPLX2ferroptosishypoxia-ischemianeurobehavioral phenotypenicotinamide adenine dinucleotide

Identifiers

PMID40247039
PMCPMC12373902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.