Evidence map›Paper›PMID 40247010›Full record

ArticleScientific reports2025

The relationship between state anxiety of surrogate decision-makers and decision-making duration in acute ischemic stroke thrombolysis.

Caixia Yang, Keke Ma, Lina Guo, Yapeng Li, Wenfeng Fan, Renke Gao, Yuanli Guo

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Caixia YangNeurology Department, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou City, 450000, Henan Province, China.
Keke MaNeurology Department, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou City, 450000, Henan Province, China.
Lina GuoNeurology Department, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou City, 450000, Henan Province, China.
Yapeng LiNeurology Department, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou City, 450000, Henan Province, China.
Wenfeng FanSchool of Nursing and Health, Zhengzhou University, 100 Science Avenue, Zhengzhou City, 450000, Henan Province, China.
Renke GaoSchool of Nursing and Health, Zhengzhou University, 100 Science Avenue, Zhengzhou City, 450000, Henan Province, China.
Yuanli GuoNeurology Department, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East Road, Zhengzhou City, 450000, Henan Province, China. gylzd@163.com.

Funding

Development of Medical and Health 2023 Research Project on "Stroke Prevention and Treatment Technology" WKZX2023CZ0402Nursing Science Foundation of the first Affiliated Hospital of Zhengzhou University HLKY20230001
6 · The paper itself

Abstract

Intravenous thrombolysis is the preferred treatment for acute ischemic stroke (AIS). In China, obtaining written informed consent from patients or their surrogates is mandatory before administering thrombolysis, often leading to delays in treatment. This study aims to explore the relationship between the decision-making characteristics and psychological states of surrogates during thrombolysis for AIS patients. A total of 383 AIS patients and their surrogate decision-makers were recruited from the Emergency Department of the First Affiliated Hospital of Zhengzhou University between September 2021 and December 2023. Comprehensive sociodemographic and disease-related data were collected for both patients and surrogates. Surrogate decision-makers were assessed using the State-Trait Anxiety Inventory (STAI), Control Preference Scale(CPS), Wake Forest Physician Trust Scale (WFPTS), and Perceived Social Support Scale (PSS). Data were analyzed using SPSS 26.0 software. The average score of state anxiety of surrogates was 49.47 ± 9.04, indicating a relatively high level of anxiety. Specifically, the average state anxiety score of the surrogate decision-makers has already reached a moderate level, indicating significant anxiety. Additionally, 18.2% (70/383) of surrogates took more than 15 minutes to decide. There was a significant positive correlation between state anxiety scores and decision duration (r = 0.189, p < 0.001). Factors influencing surrogate anxiety included sociodemographic factors, psychological factors, patient-related factors, and decision-making process characteristics (all p < 0.05). In conclusion, the anxiety is influenced by various factors related to the decision-making process. Medical staff should address these emotional factors to reduce decision time, enhance decision quality, and expedite informed consent, thereby minimizing treatment delays.

Indexed as

AnxietyDecision MakingIschemic StrokeThrombolytic TherapyAdultAgedChinaFemaleHumansMaleMiddle AgedAcute ischemic strokeDecision-makingInfluencing factorsState anxietyThrombolysis

Identifiers

PMID40247010
PMCPMC12504575

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.