Evidence map›Paper›PMID 40246920›Full record

ArticleScientific reports2025

Vaccination burnout impedes the compliance with multiple-dose administration of vaccines.

Xueying Fan, Yangguo Zhao, Xinyu Zhang, Shunran Li, Fan Wu, Mingting Cui, Ying Ye, Wangmu Duoji, Shiqiang Jiang, Jianhui Yuan and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Xueying Fan *Shenzhen Key Laboratory of Pathogenic Microbes and Biosafety, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Yangguo Zhao *Shenzhen Key Laboratory of Pathogenic Microbes and Biosafety, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Xinyu Zhang *Shenzhen Key Laboratory of Pathogenic Microbes and Biosafety, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Shunran LiShenzhen Key Laboratory of Pathogenic Microbes and Biosafety, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Fan WuShenzhen Key Laboratory of Pathogenic Microbes and Biosafety, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Mingting CuiShenzhen Key Laboratory of Pathogenic Microbes and Biosafety, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Ying YeShenzhen Key Laboratory of Pathogenic Microbes and Biosafety, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.
Wangmu DuojiTibet Center for Disease Control and Prevention, Lhasa, 850000, China.
Shiqiang JiangNanshan District Center for Disease Control and Prevention, Shenzhen, 518000, China.
Jianhui YuanNanshan District Center for Disease Control and Prevention, Shenzhen, 518000, China. jianhui_yuan@126.com.
Caijun SunShenzhen Key Laboratory of Pathogenic Microbes and Biosafety, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China. suncaijun@mail.sysu.edu.cn.

Funding

National Key Research and Development Program of China 2021YFC2300103, 2022YFE0203100Sanming Project of Medicine in Shenzhen Nanshan No. SZSM202103008Shenzhen Key Laboratory of Pathogenic Microbes and Biosafety ZDSYS20230626091203007The Science and Technology Planning Project of Guangdong Province, China 2021B1212040017
6 · The paper itself

Abstract

Timely and complete administration of multiple-dose vaccines is essential to guarantee the efficacy. Our study aimed to investigate how people's vaccination attitudes changed over the course of the multi-dose vaccination schedule and comprehensively reported a phenomenon of vaccination burnout. The participants' vaccination burnout levels were quantified by our designed vaccination burnout scale. This study is a retrospective cross-sectional study. Among 3068 valid participants, 2991 had finished the routine two shots of COVID-19 vaccine, and 2367 had a positive attitude towards the primary doses of vaccination. Notably, 232 participants who previously had a positive attitude towards primary doses of vaccination refused to take additional multiple shots, and another 83 had changed their positive attitudes to negative, despite having taken the third shot. Participants whose attitudes or behaviors had changed had higher scores of vaccination burnout than those who still maintained a positive attitude (Z=-8.491, P < .001). The frequency of actively paying attention to the related disease news, occupation, monthly income, and residence of the participants were key factors associated with the vaccination burnout. Interventions should be implemented to alleviate the exhausted attitudes and improve people's compliance with vaccination schedules against the future pandemic.

Indexed as

Burnout, PsychologicalCOVID-19COVID-19 VaccinesPatient ComplianceVaccinationAdultAgedCross-Sectional StudiesFemaleHumansImmunization ScheduleMaleMiddle AgedRetrospective StudiesSARS-CoV-2Surveys and QuestionnairesCOVID-19 VaccinesCase studyCOVID-19 vaccineMultiple-dose vaccinationPublic healthVaccination burnout

Identifiers

PMID40246920
PMCPMC12006531

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.