Evidence map›Paper›PMID 40246860›Full record

ArticleNature communications2025

Heterocycle-based dynamic covalent chemistry for dynamic functional materials.

Zeyu Ma, Siyu Pan, Yang Yang, Yuan Zeng, Bo Wang, Yen Wei, Lei Tao

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zeyu MaThe Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084, P. R. China.
Siyu PanThe Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084, P. R. China.
Yang YangInstitute of Nuclear and New Energy Technology, Tsinghua University, Beijing, 100084, China.
Yuan ZengThe Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084, P. R. China.
Bo WangInstitute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, 100193, China. youxihema@gmail.com.
Yen WeiThe Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084, P. R. China.ORCID http://orcid.org/0000-0001-5950-0163
Lei TaoThe Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084, P. R. China. leitao@tsinghua.edu.cn.ORCID http://orcid.org/0000-0002-1735-6586

Funding

Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) 2022YFB3804901National Science Foundation of China | Major Research Plan 22471140
6 · The paper itself

Abstract

Dynamic covalent chemistry, which renders reusable and degradable thermoset polymers, is a promising tool for solving the global problem of plastic pollution. Although dynamic covalent chemistry can construct dynamic polymer networks, it rarely introduces other functions into polymers, which limits the development of dynamic functional materials. Herein, we develop heterocycle-based dynamic covalent chemistry and demonstrate the reversibility of the aza-Michael addition reaction between functional heterocycle dihydropyrimidin-2(1H)-thione and electron-deficient olefins. Our method produces a degradable linear polymer and recyclable and self-healable crosslinked polymers similar to traditional dynamic covalent chemistry, but the heterocycles endow the polymer with excellent ultraviolet-blocking and high-energy blue light-blocking abilities, and tunable fluorescence and phosphorescence properties. These are difficult to create with ordinary dynamic covalent chemistry. This proof-of-concept study provides insights into heterocycle-based dynamic reactions, and may prompt the development of dynamic chemistry and dynamic functional materials.

Identifiers

PMID40246860
PMCPMC12006384

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.