Evidence map›Paper›PMID 40246791›Full record

ReviewJournal of internal medicine2025

Breaking with the status quo in end-of-life care through de-implementation.

Chetna Malhotra, Ellie Bostwick Andres

Abstract readReview
In one paragraph

Review in Journal of internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chetna MalhotraLien Centre for Palliative Care, Duke-NUS Medical School, Singapore, Singapore.ORCID 0000-0002-5380-0525
Ellie Bostwick AndresLien Centre for Palliative Care, Duke-NUS Medical School, Singapore, Singapore.ORCID 0000-0001-9086-8222

Funding

National Medical Research Council MOH-1031National Medical Research Council MOH-HCSAINV21jun-0002
6 · The paper itself

Abstract

This paper addresses the challenge of de-implementing low-value care practices in the end-of-life (EOL) context, where burdensome interventions often offer marginal life-extending benefits, incur substantial costs and diminish quality of life. We examine the complexities involved in discontinuing such practices, including clinician biases, institutional cultures favouring aggressive interventions and communication barriers among healthcare providers, patients and families. We discuss how de-implementation at the EOL is unique from other contexts, prioritizing patient-centred care rather than cost reduction. Effective communication and support for patients, families and clinicians is essential, as de-implementation often represents a shift towards what patients and families value. Our review of existing evidence underscores the need for the development and evaluation of de-implementation strategies tailored to EOL care, as described. De-implementation at the EOL requires sensitivity to the complex, emotional nature of EOL care and provides a unique opportunity to integrate palliative care approaches and improve overall EOL care quality.

Indexed as

Palliative CareTerminal CareCommunicationHumansPatient-Centered CareQuality of Health CareQuality of Lifede‐implementationend‐of‐life carelow‐value carepatient‐centred careterminal care

Identifiers

PMID40246791
PMCPMC12239056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.