Evidence map›Paper›PMID 40246768›Full record

ArticleCancer causes & control : CCC2025

Leveraging existing cohort studies of Mexican women to better understand Hispanic health and cancer risk.

Dalia Stern, Liliana Gomez-Flores-Ramos, Britton Trabert, V Wendy Setiawan, Loïc Le Marchand, Henry Gomez, Paul A Scheet, Humberto Parada, Amber Pirzada, Martin Lajous and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer causes & control : CCC, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dalia SternSECIHTI - Center for Research on Population Health, National Institute of Public Health, Fray Pedro de Gante 12, Belisario Domínguez Secc 16, Tlalpan, 14080, Ciudad de México, Mexico.ORCID http://orcid.org/0000-0003-3779-6543
Liliana Gomez-Flores-RamosSECIHTI - Center for Research on Population Health, National Institute of Public Health, Fray Pedro de Gante 12, Belisario Domínguez Secc 16, Tlalpan, 14080, Ciudad de México, Mexico. Liliana.gomez@insp.mx.ORCID http://orcid.org/0000-0002-4617-639X
Britton TrabertDepartment of Obstetrics and Gynecology, University of Utah, and Huntsman Cancer Institute at the University of Utah, 30 N 1900 E, Salt Lake City, UT, 84132, USA.
V Wendy SetiawanDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, 1845 N Soto St, Los Angeles, CA, 90032, USA.
Loïc Le MarchandPopulation Sciences in the Pacific Program, University of Hawaii Cancer Center, 701 Ilalo Street, Honolulu, HI, 96813, USA.
Henry GomezDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, 1155 Pressler St., Unit 1340, Houston, TX, 77030, USA.
Paul A ScheetDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, 1155 Pressler St., Unit 1340, Houston, TX, 77030, USA.
Humberto ParadaDivision of Epidemiology and Biostatistics, School of Public Health, San Diego State University, 5500 Campanile Drive, San Diego, CA, 92182, USA.
Amber PirzadaInstitute for Minority Health Research, University of Illinois Chicago, 1819 West Polk Street, Chicago, IL, 60612, USA.
Martin LajousDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, 655 Huntington Ave, Boston, MA, 02115, USA.
Leslie V FarlandDepartment of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, 1295 N. Martin Ave, Tucson, AZ, 85724, USA.ORCID http://orcid.org/0000-0001-7455-8531

Funding

The Research Infrastructure Core of SDSU HealthLINK Center for Transdisciplinary Health Disparities ResearchU54MD012397 · NIMHD · SAN DIEGO STATE UNIVERSITY · PI Kristen Jennifer Wells · 2018 to 2026
$39.0M
Understanding Population Differences in Cancer: The MEC StudyU01CA164973 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI HAIMAN, CHRISTOPHER ALAN, LE MARCHAND, LOIC · 2015 to 2025
$37.4M
SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI George S Watts · 1994 to 2026
$36.7M
Building Capacity and Infrastructure for Population Health and Health Disparities Research at San Diego State UniversityS21MD010690 · NIMHD · SAN DIEGO STATE UNIVERSITY · PI AYALA, GUADALUPE X, CASTILLO, JOSE E · 2016 to 2020
$10.0M
TALENT Shared Resources CoreU54CA285115 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI James D Murphy · 2023 to 2026
$6.6M
Research Education CoreU54CA285117 · NCI · SAN DIEGO STATE UNIVERSITY · PI Humberto Parada · 2023 to 2026
$6.2M
Infertility and Long-Term Health Outcomes Among Hispanic Women with Mexican HeritageR01HD114871 · NICHD · UNIVERSITY OF ARIZONA · PI Leslie V Farland · 2024 to 2026
$1.4M
Red Blood Cell Polyunsaturated Fatty Acids and Breast Cancer Mortality in the Women's Healthy Eating and Living (WHEL) StudyK01CA234317 · NCI · SAN DIEGO STATE UNIVERSITY · PI PARADA, HUMBERTO · 2019 to 2023
$928k
HISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–
National Institute of Child Health and Human Development HD114871NCI NIH HHS CA234317NCI NIH HHS K01 CA234317NCI NIH HHS U01 CA164973NCI NIH HHS U54 CA285115NCI NIH HHS U54 CA285117NHGRI NIH HHS HHSN268201300003CNHLBI NIH HHS HHSN268201300003INHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NICHD NIH HHS R01 HD114871NIEHS NIH HHS P30 ES006694NIMHD NIH HHS MD012397NIMHD NIH HHS S21 MD010690NIMHD NIH HHS U54 MD012397
6 · The paper itself

Abstract

backgroundHispanics have been historically underrepresented in epidemiologic cancer research. Existing cohort studies focused on recruiting Hispanic participants have been relatively small, making studying cancer outcomes challenging. Therefore, we aimed to compare the distribution of cancer risk factors among Hispanic women of Mexican heritage (HWMH) participating in existing cohorts to explore the possibility of future data pooling efforts.

methodsWe used baseline data of HWMH from three US-based studies, the Mexican American Cohort (MAC; n = 19,797; 2001-2017), the Multiethnic Cohort (MEC; n = 18,007; 1993-1996), and the Hispanic Community Health Study/Study of Latinos (HCHS/SOL; n = 4,022; 2008-2011), and one study from Mexico, the Mexican Teachers' Cohort (MTC; n = 115,275; 2006-2008).

resultsParticipants in MEC (59.5y) were older on average than MAC (40.9y), HCHS/SOL (45.5y), and MTC (42.6y) at enrollment. Most MAC (77.6%) and HCHS/SOL (85.4%) participants spoke Spanish as their primary language. Age at menarche (12.5-13.1y), age at menopause (45.8-47.9y), and smoking prevalence (~ 10%) was similar across studies. Parity was higher in MAC (3.8) and MEC (4.1) compared to HCHS/SOL (3.2) and MTC (2.5). Ever use of oral contraceptives was more frequent in HCHS/SOL (63.5%) compared to MTC (45.6%), MAC (37.9%), and MEC (35.2%). Obesity, diabetes, and hypertension were more common in the US cohorts.

conclusionThis comparative study demonstrates the ability to harmonize data and provide information for future pooling projects across cohorts to evaluate cancer outcomes. Similarities and differences in characteristics across cohorts can be leveraged to better understand health disparities in HWMH.

Indexed as

Hispanic or LatinoMexican AmericansNeoplasmsAdultAgedCohort StudiesFemaleHumansMexicoMiddle AgedRisk FactorsUnited StatesCancer epidemiologyCohort studiesHispanic women of Mexican heritage

Identifiers

PMID40246768
PMCPMC12707317

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.