Evidence map›Paper›PMID 40246758›Full record

SynthesisJournal of neurology2025

Association between weather conditions and migraine: a systematic review and meta-analysis.

Shiqin Li, Qian Liu, Mengmeng Ma, Jinghuan Fang, Li He

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shiqin Li *Department of Neurology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Qian Liu *Department of Neurology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Mengmeng MaDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Jinghuan FangDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, 610041, China. jinghuan_fang@126.com.
Li HeDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, 610041, China. heli2003new@126.com.ORCID http://orcid.org/0000-0002-2034-1027

Funding

China Postdoctoral Science Foundation 2022M722265National Natural Science Foundation of China 82101395National Natural Science Foundation of China 82271360National Natural Science Foundation of China 82301404Postdoctor Research Fund of West China Hospital, Sichuan University 2023HXBH061Sichuan Science and Technology program 2024NSFSC1633
6 · The paper itself

Abstract

backgroundPrevious studies have linked migraine to weather conditions, but variations in the factors examined and inconsistent focus have complicated comparisons. This underscores the need for a more comprehensive and clearer analysis.

methodsStudies published before December 2024 on the association between weather and migraine were searched from PubMed, Embase, Web of Science, and Cochrane. Meta-analyses based on effect sizes were performed using Review Manager version 5.4.1.

resultsA total of 31 studies were included in the meta-analyses. It revealed a significant association between migraine attack and weather changes reported as a trigger factor (RD = 0.47, 95% CI = 0.40-0.54). Additionally, specific weather factors, such as temperature (OR = 1.15, 95% CI = 1.02-1.29) and ambient pressure (OR = 1.07, 95% CI = 1.01-1.15), were significantly associated with migraine attacks, while humidity (OR = 1.04, 95% CI = 0.97-1.11) did not show a significant association. Moreover, increased levels of air pollutants, including PM10 (OR = 1.07, 95% CI = 1.03-1.11), PM2.5 (OR = 1.04, 95% CI = 1.01-1.06), NO

conclusionsThis meta-analysis revealed that weather changes are significant trigger factors for migraine, with temperature and ambient pressure playing notable roles in this association. Additionally, increased levels of air pollutants are linked to a higher risk of migraine attacks. These findings could lead to new interventions for patients who are weather-sensitive and offer fresh perspectives for future research into the pathogenesis of migraine.

Indexed as

Air PollutantsMigraine DisordersWeatherHumansAir PollutantsMeta-analysisMigraineSystematic reviewWeather conditions

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.