Evidence map›Paper›PMID 40246566›Full record

ArticleBMJ open2025

ARFID InitiativE Sweden (ARIES): study protocol for a large-scale genetic and registry-linked cohort study on avoidant/restrictive food intake disorder.

Liv Hog, Bengt T Fundin, Erik Everett Palm, Annelie Billger, Cynthia M Bulik, Afrouz Abbaspour, Lisa Dinkler

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liv HogDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.ORCID http://orcid.org/0009-0004-7249-4772
Bengt T FundinDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Erik Everett PalmDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-9647-577X
Annelie BillgerDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Cynthia M BulikDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Afrouz AbbaspourDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-1337-0102
Lisa DinklerDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden lisa.dinkler@ki.se.ORCID http://orcid.org/0000-0002-9901-4984

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe ARFID InitiativE Sweden (ARIES) investigates the genetic and environmental factors contributing to avoidant/restrictive food intake disorder (ARFID) in children and adolescents aged 6-14 years. ARIES will establish a national biobank and research registry. It aims to provide data for immediate research and track ARFID outcomes and clarify genetic links between ARFID and other conditions and analyse the gut microbiome to guide nutrition interventions. METHODS AND ANALYSIS: The study will involve 1500 Swedish children and adolescents with ARFID and a control group of 500 Swedish children and adolescents without ARFID. Parents/guardians and their children will complete online questionnaires assessing ARFID and other eating disorder (ED) pathology, co-occurring conditions, quality of life and parental stress and ED pathology. All participants will provide a saliva sample for comprehensive genetic analyses. Additionally, a subset of participants will provide a stool sample to investigate the gut microbiome in ARFID. ETHICS AND DISSEMINATION: ARIES was approved by the Swedish Ethical Review Authority (Dnr 2023-04638). All participants will give assent and their parents will complete informed consent. Data will be made available by the authors on reasonable request. Findings will be published in scientific journals and shared with the public and stakeholders in accessible ways, for example, via social media.

Indexed as

Avoidant Restrictive Food Intake DisorderFeeding and Eating DisordersAdolescentChildCohort StudiesFemaleGastrointestinal MicrobiomeHumansMaleQuality of LifeRegistriesResearch DesignSurveys and QuestionnairesSwedenEating disordersGENETICSMENTAL HEALTHPSYCHIATRY

Identifiers

PMID40246566
PMCPMC12007039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.