Evidence map›Paper›PMID 40246551›Full record

ArticleeNeuro2025

Time Varying Encoding of Grasping Type and Force in the Primate Motor Cortex.

Adriana Moreno, Victor de Lafuente, Hugo Merchant

Abstract read
In one paragraph

Article in eNeuro, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Distinct Neural Modes Carry Information About Attempted Grasp Timing and Force in the Sensorimotor Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adriana MorenoInstituto de Neurobiología, UNAM, Campus Juriquilla, Querétaro 76230, México.
Victor de LafuenteInstituto de Neurobiología, UNAM, Campus Juriquilla, Querétaro 76230, México hugomerchant@unam.mx lafuente@unam.mx.ORCID https://orcid.org/0000-0002-1047-1354
Hugo MerchantInstituto de Neurobiología, UNAM, Campus Juriquilla, Querétaro 76230, México hugomerchant@unam.mx lafuente@unam.mx.ORCID https://orcid.org/0000-0002-3488-9501

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The primary motor cortex (M1) is strongly engaged by movement planning and execution. However, the role of M1 activity in voluntary grasping is still not completely understood. Here we analyze recordings of M1 neurons during the execution of a delayed reach-to-grasp task, where monkeys had to actively grasp an object with either a side or a precision grip, and then pull it with a low or high amount of force. Single cell and neural populations analyses showed that grip type was robustly and specifically encoded by a large population of neurons, while force level was weakly and transiently encoded within mixed-selective neurons that also encoded grip type. Notably, the grip type was stably decoded from motor cortical populations during the preparation and execution epochs of the task. Our results are consistent with the idea that planning and performing specific grasping movements are high-level skills that strongly engage M1 neurons, while the execution of pulling force might be prominently encoded at lower stages of the motor system.

Indexed as

Hand StrengthMotor ActivityMotor CortexNeuronsPsychomotor PerformanceAnimalsMacaca mulattaMaleTime Factorsgraspingmotor cortexmovement preparation

Identifiers

PMID40246551
PMCPMC12037165

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.