ArticleBreast (Edinburgh, Scotland)2025
Analysis of factors influencing chemotherapy-induced peripheral neuropathy in breast cancer patients using a random forest model.
Article in Breast (Edinburgh, Scotland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Comparative predictive performance of three machine learning algorithms for acute radiation enteritis risk among patients with cervical cancer undergoing radiotherapy: A prospective cohort study.Asia-Pacific journal of oncology nursing · 2026Article
- Large fiber contribution to symptoms in chemotherapy-induced peripheral neuropathy in cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Machine learning-based prediction model for omental metastasis in right-sided colon cancer patients: a retrospective multicenter study.International journal of colorectal disease · 2025Article
- Analysis of factors influencing innovative behaviors of intensive care unit nurses using a random forest model-a multicentre cross-sectional study.BMC nursing · 2025Article
- Correlation of nutrition with neuropathy in ovarian cancer patients.Bioinformation · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to analyze the factors influencing chemotherapy-induced peripheral neuropathy (CIPN) in breast cancer patients, identify modifiable factors, and provide a theoretical basis for targeted interventions.
methodsA total of 542 patients with breast cancer who were hospitalized for chemotherapy in multiple hospitals from September 2022 to September 2023 were selected as the study objects. Data were collected using questionnaires covering demographic characteristics, disease-related information, lifestyle, and psychological status. Lasso-logistic regression was employed to identify influencing factors, and a random forest model was used to rank the importance of variables.
resultsLasso-logistic regression analysis identified age, BMI, cumulative chemotherapy dose, hypertension, physical activity level, and depression as significant factors associated with CIPN (P < 0.05). The variable importance ranking from the random forest model was as follows: age, BMI, cumulative chemotherapy dose, physical activity, hypertension, and depression.
conclusionEarly identification of high-risk CIPN patients is crucial for guiding clinical nursing practices. These findings provide a foundation for the management and intervention of CIPN in breast cancer patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.