Access to gene therapy for sickle cell disease in Africa.

Julie Makani, Daima Bukini, Stella Malangahe, Staci D Arnold, Sonal Patel, Aisha Rifai, Grace Moshi

Abstract read

In one paragraph

Article in EBioMedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julie MakaniSickle Cell Programme, Department of Haematology and Blood Transfusion, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania; SickleInAfrica Clinical Coordinating Center, SickleInAfrica, Dar es Salaam, Tanzania; Imperial College London, London, UK. Electronic address: jmakani@blood.ac.tz.

Daima BukiniSickle Cell Programme, Department of Haematology and Blood Transfusion, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania; SickleInAfrica Clinical Coordinating Center, SickleInAfrica, Dar es Salaam, Tanzania; Berman Institute of Bioethics, Johns Hopkins Bloomberg School of Public Health, USA.

Stella MalangaheBenjamin Mkapa Hospital, Dodoma, Tanzania.

Staci D ArnoldEmory University, Atlanta, USA.

Sonal PatelAga Khan Hospital, Dar es Salaam, Tanzania.

Aisha RifaiSickle Cell Programme, Department of Haematology and Blood Transfusion, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.

Grace MoshiSickle Cell Programme, Department of Haematology and Blood Transfusion, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania; KK Women's & Children's Hospital, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40245493

DOI10.1016/j.ebiom.2025.105713

PMCPMC12143207

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.