Evidence map›Paper›PMID 40245193›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Ultrasound Cavitation Enables Rapid, Initiator-Free Fabrication of Tough Anti-Freezing Hydrogels.

Yixun Cheng, Stephen Lee, Yihang Xiao, Shou Ohmura, Louis-Jacques Bourdages, Justin Puma, Zixin He, Zhen Yang, Jeremy Brown, Jean Provost and 1 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Ultrasound-responsive composite hydrogels: Design rules for spatiotemporally controlled drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Underwater Instant Adhesive Hydrogel Interfaces for Robust Biosensing on Diverse Species.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yixun ChengDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St West, Montreal, Quebec, H3A 0C3, Canada.ORCID https://orcid.org/0009-0007-3322-4229
Stephen LeeDepartment of Engineering Physics, Polytechnique Montreal, 2500 Chemin de Polytechnique, Montreal, Quebec, H3T 1J4, Canada.
Yihang XiaoDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St West, Montreal, Quebec, H3A 0C3, Canada.
Shou OhmuraDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St West, Montreal, Quebec, H3A 0C3, Canada.
Louis-Jacques BourdagesDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St West, Montreal, Quebec, H3A 0C3, Canada.
Justin PumaDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St West, Montreal, Quebec, H3A 0C3, Canada.
Zixin HeDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St West, Montreal, Quebec, H3A 0C3, Canada.
Zhen YangDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St West, Montreal, Quebec, H3A 0C3, Canada.
Jeremy BrownDepartment of Electrical and Computer Engineering, Dalhousie University, 1459 Oxford Street, Halifax, Nova Scotia, B3H 4R2, Canada.
Jean ProvostDepartment of Engineering Physics, Polytechnique Montreal, 2500 Chemin de Polytechnique, Montreal, Quebec, H3T 1J4, Canada.
Jianyu LiDepartment of Mechanical Engineering, McGill University, 817 Sherbrooke St West, Montreal, Quebec, H3A 0C3, Canada.ORCID https://orcid.org/0000-0002-1128-6804

Funding

Develop a wireless, skin-conformable and dual-sensing wearable system in support of voice and upper airway telehealth careR01DC021461 · NIDCD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Wei Gao, Jianyu Li · 2024 to 2026
$1.8M
Fonds de recherche du Québec - Nature et technologies FRQ-NT 2024-NOVA-344903Natural Sciences and Engineering Research Council of Canada RGPIN-2024-04925NIDCD NIH HHS R01 DC021461NIH HHS R01DC021461
6 · The paper itself

Abstract

Hydrogels are often synthesized with thermal or photo-initiated gelation, leaving alternative energy sources less explored. While ultrasound has been used for polymer synthesis and mechanochemistry, its application through cavitation for hydrogel synthesis as a constructive force is rare, and the underlying sonochemical mechanisms are poorly understood. Here, the application and mechanism of ultrasound cavitation for rapid, initiator-free, and oxygen-tolerant fabrication of tough anti-freezing hydrogels is reported. By incorporating polyol solvents and interpenetrating polymers into the gelling solution, radical generation is amplified and network formation is enhanced. Using tough polyacrylamide-alginate hydrogels as a model system, rapid gelation (as fast as 2 minutes) and high fracture toughness (up to 600 J m

Indexed as

hydrogelsmechanical propertiesradical polymerizationsonochemistryultrasound

Identifiers

PMID40245193
PMCPMC12165056

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.