ArticleScience (New York, N.Y.)2025
Structural basis for nucleolin recognition of
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Article in Science (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26citing papers in PubMed
–field-weighted citation impact
What it found
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Who cites it
26 citing papers in PubMed.
- Massively parallel characterization of RNA G-quadruplex stability and molecular recognition.Nucleic acids research · 2026Article
- The G-force in the genome: Unknowns on the functional flairs of DNA G-quadruplexes.PLoS biology · 2026Article
- Molecular glue that stabilizes the LRPPRC-MET-G4 interaction complex to drive MET downregulation.Nature communications · 2026Article
- Precise discrimination of G-quadruplex conformation by chiral nanoassembly with photo-reversibility.Nature communications · 2026Article
- A small molecule disrupts G4-STAT1 interaction and synergizes with olaparib to drive cancer cell death.Nucleic acids research · 2026Article
- Dual-mode aptamer-driven biosensing platform for ultrasensitive and mutation-resilient detection of the SARS-CoV-2 nucleocapsid protein.Genes & diseases · 2026Article
- G4-Ligand-Directed PROTACs Unveil DR1 as a Novel Ligand-Co-Binding G4-Protein and Reshape G4-Dependent Transcription.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- TOP1α-mediated stabilization of CYP82C4 G-quadruplex DNA represses lateral root primordium initiation in Arabidopsis.Nature plants · 2026Article
- Characterizations of G-Quadruplex RNA-Protein Interactions in Living Cells.Analytical chemistry · 2026Article
- The cellular landscape of i-motifs: genomic insights, methodological challenges, and the road ahead.Genome biology · 2026Review
- Unraveling the molecular mechanisms of vimentin interaction with G-quadruplex repeats.Nucleic acids research · 2026Article
- Dissecting the Binding Interactions of the Chromatin Remodeler SMARCA4 with G-Quadruplex DNA.Biochemistry · 2026Article
- Mechanistic insights into PCBP1-driven unfolding of selected i-motif DNA at GNature communications · 2026Article
- Indirect identification of genomic G-quadruplexes via a small protein probe that specifically recognizes C-rich single-stranded DNA.Nucleic acids research · 2026Article
- Glutamic Acid-Chelated Cobalt Stabilizes G-Quadruplexes and Selectively Suppresses Hepatocellular Carcinoma Growth.Oncology research · 2026Article
- Differences and Similarities in Protein and Nucleic Acid Structures and Their Biological Interactions.Current issues in molecular biology · 2025Review
- Alternative Splicing: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets.MedComm · 2025Review
- Degradation of G-Quadruplex-Binding Proteins by G4L-PROTAC via Quaternary Complex Formation.Angewandte Chemie (International ed. in English) · 2025Article
- Age-associated G-quadruplex accumulation and DDX5 loss shape chromatin landscapes in human astrocytes.Research square · 2025Article
- The Hippo-YAP signaling pathway promotes hepatocellular carcinoma progression by inducing FHL3 expression.Cell death & disease · 2025Article
Corrections and comments
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Authors and funding
20 authors.
Luying ChenBorch Department of Medicinal Chemistry and Molecular Pharmacology, College of .Pharmacy, Purdue University, West Lafayette, IN, USA.ORCID 0000-0001-5136-4945
Jonathan DickerhoffBorch Department of Medicinal Chemistry and Molecular Pharmacology, College of .Pharmacy, Purdue University, West Lafayette, IN, USA.ORCID 0000-0002-3197-9472
Ke-Wei ZhengSchool of Biomedical Sciences, Hunan University, Changsha, China.ORCID 0000-0002-4110-4776
Satchal ErramilliDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA.ORCID 0000-0001-8694-7681
Hanqiao FengLaboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-3488-0600
Guanhui WuBorch Department of Medicinal Chemistry and Molecular Pharmacology, College of .Pharmacy, Purdue University, West Lafayette, IN, USA.ORCID 0000-0003-4659-8717
Buket OnelBorch Department of Medicinal Chemistry and Molecular Pharmacology, College of .Pharmacy, Purdue University, West Lafayette, IN, USA.
Yuwei ChenR. Ken Coit College of Pharmacy, University of Arizona, Tucson, AZ, USA.ORCID 0009-0000-1198-3928
Kai-Bo WangBorch Department of Medicinal Chemistry and Molecular Pharmacology, College of .Pharmacy, Purdue University, West Lafayette, IN, USA.ORCID 0000-0002-2934-9906
Megan CarverR. Ken Coit College of Pharmacy, University of Arizona, Tucson, AZ, USA.ORCID 0000-0003-3637-5253
Clement LinBorch Department of Medicinal Chemistry and Molecular Pharmacology, College of .Pharmacy, Purdue University, West Lafayette, IN, USA.
Saburo SakaiBorch Department of Medicinal Chemistry and Molecular Pharmacology, College of .Pharmacy, Purdue University, West Lafayette, IN, USA.ORCID 0000-0002-3809-0254
Jun WanDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.ORCID 0000-0001-9286-6562
Charles VinsonLaboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-7453-1793
Laurence HurleyR. Ken Coit College of Pharmacy, University of Arizona, Tucson, AZ, USA.
Anthony A KossiakoffDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA.
Nanjie DengDepartment of Chemistry and Physical Sciences, Pace University, New York, NY, USA.ORCID 0000-0001-8805-3526
Yawen BaiLaboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-3239-1109
Nicholas NoinajMarkey Center for Structural Biology, Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.ORCID 0000-0001-6361-2336
Danzhou YangBorch Department of Medicinal Chemistry and Molecular Pharmacology, College of .Pharmacy, Purdue University, West Lafayette, IN, USA.ORCID 0000-0001-7489-7111
Funding
Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI ANDREW D MESECAR · 1985 to 2026
$43.4MChaperone-Assisted Structure Determination of Membrane ProteinsR01GM117372 · NIGMS · UNIVERSITY OF CHICAGO · PI ANTHONY A KOSSIAKOFF · 2016 to 2026
$4.0MTargeting MYC promoter G-quadruplex for MYC inhibition by IndenoisoquinolinesR01CA177585 · NCI · UNIVERSITY OF ARIZONA · PI SINTIM, HERMAN O, YANG, DANZHOU · 2014 to 2025
$4.0MNucleolin recognition of MYC promoter G-quadruplex and its role in MYC regulation by MycG4-ligandsU01CA240346 · NCI · PURDUE UNIVERSITY · PI YANG, DANZHOU · 2020 to 2024
$2.1MStructural Characterization of the TOC Protein Translocon MachineryR01GM127896 · NIGMS · PURDUE UNIVERSITY · PI NOINAJ, NICHOLAS · 2018 to 2022
$1.5MUnraveling the mechanism by which the BAM complex mediates OMP biogenesisR01GM127884 · NIGMS · PURDUE UNIVERSITY · PI NOINAJ, NICHOLAS · 2019 to 2022
$1.2MG-quadruplexes formed in human oncogene promoters and their drug complexesR01CA122952 · NCI · UNIVERSITY OF ARIZONA · PI YANG, DANZHOU · 2007 to 2011
$875kNCI NIH HHS P30 CA023168NCI NIH HHS R01 CA122952NCI NIH HHS R01 CA177585NCI NIH HHS U01 CA240346NIGMS NIH HHS R01 GM117372NIGMS NIH HHS R01 GM127884NIGMS NIH HHS R01 GM127896
Abstract
The
Indexed as
Genes, mycG-QuadruplexesNucleolinPromoter Regions, GeneticProto-Oncogene Proteins c-mycRNA-Binding ProteinsCrystallography, X-RayHumansModels, MolecularPotassiumProtein BindingProtein DomainsNucleolinPotassiumProto-Oncogene Proteins c-mycRNA-Binding Proteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.