ArticleAnnals of clinical and translational neurology2025
Spinal Cord Abnormalities in Early Pediatric Multiple Sclerosis.
Article in Annals of clinical and translational neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Smouldering disease in paediatric-onset multiple sclerosis.EBioMedicine · 2025Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spinal cord lesions and atrophy in the cervical region are common in adult multiple sclerosis (MS) and correlate with disability. Whether similar abnormalities occur in pediatric MS patients is largely unknown. Clinical and MRI evaluations were performed in 38 pediatric MS patients and 13 healthy controls (HC). No significant differences in upper cervical cord area were found between MS patients and HC or between patients with and without lesions. Patients with lesions showed increased cord volume, co-localizing with lesions, likely reflecting inflammation. Our results suggest that upper cord atrophy is not a prominent feature in early pediatric MS, underscoring the inflammation-driven characteristic of these patients.
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