ArticleAnnals of clinical and translational neurology2025
Cerebral Amyloid Angiopathy Is Associated With Higher R
Md Tahmid Yasar, Arnold M Evia, Mahir Tazwar, Sue E Leurgans, David A Bennett, Julie A Schneider, Konstantinos Arfanakis
Abstract read
In one paragraphArticle in Annals of clinical and translational neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Md Tahmid YasarDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, USA.
Arnold M EviaRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Mahir TazwarDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, USA.
Sue E LeurgansRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
David A BennettRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Julie A SchneiderRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Konstantinos ArfanakisDepartment of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, USA.ORCID 0000-0001-9705-597X Funding
SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LEURGANS, SUE E. · 1991 to 2020
$49.1MEPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3MRush Alzheimer's Disease Research CenterP30AG072975 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI Lisa L Barnes, Julie A. Schneider · 2021 to 2026
$24.7MRISK FACTORS, PATHOLOGY, AND CLINICAL EXPRESSIONS OF ADR01AG015819 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 1998 to 2024
$21.4MCharacterizing TDP-43 related hippocampal degeneration and memory loss in agingR01AG067482 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI SCHNEIDER, JULIE A. · 2020 to 2024
$6.8MRacial Differences in Late-Life Cognitive Decline and Risk of Alzheimer's DiseaseRF1AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2016 to 2019
$6.6MVascular-immune mechanisms of cerebral amyloid angiopathy and Alzheimer's pathologyRF1NS139975 · NINDS · J. DAVID GLADSTONE INSTITUTES · PI ARFANAKIS, KONSTANTINOS, BLURTON-JONES, MATHEW MARK · 2024 to 2024
$5.4MMRI markers of brain aging and risk factors for cognitive decline in older African AmericansR01AG056405 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2018 to 2023
$3.6MLongitudinal validation of cerebral small vessel disease biomarkers in diverse community-based older adults without dementiaU01NS100599 · NINDS · RUSH UNIVERSITY MEDICAL CENTER · PI ARFANAKIS, KONSTANTINOS, SCHNEIDER, JULIE A. · 2023 to 2025
$3.5MMultimodal MRI biomarkers of small vessel disease for older persons with and without dementia.UH3NS100599 · NINDS · RUSH UNIVERSITY MEDICAL CENTER · PI ARFANAKIS, KONSTANTINOS, SCHNEIDER, JULIE A. · 2018 to 2020
$3.5MIn-vivo MRI-based prediction of TDP43 pathology in agingR01AG064233 · NIA · ILLINOIS INSTITUTE OF TECHNOLOGY · PI ARFANAKIS, KONSTANTINOS, SCHNEIDER, JULIE A. · 2019 to 2023
$3.3MComprehensive Longitudinal Probabilistic Atlas of the Brain of Older Adults Without DementiaR01AG052200 · NIA · ILLINOIS INSTITUTE OF TECHNOLOGY · PI ARFANAKIS, KONSTANTINOS · 2016 to 2020
$2.5MNIA NIH HHS P30 AG010161NIA NIH HHS P30AG010161NIA NIH HHS P30 AG072975NIA NIH HHS P30AG072975NIA NIH HHS R01 AG015819NIA NIH HHS R01AG015819NIA NIH HHS R01 AG017917NIA NIH HHS R01AG017917NIA NIH HHS R01 AG052200NIA NIH HHS R01AG052200NIA NIH HHS R01 AG056405NIA NIH HHS R01AG056405NIA NIH HHS R01 AG064233NIA NIH HHS R01AG064233NIA NIH HHS R01 AG067482NIA NIH HHS R01AG067482NIA NIH HHS RF1 AG022018NIA NIH HHS RF1AG022018NINDS NIH HHS RF1 NS139975NINDS NIH HHS RF1NS139975NINDS NIH HHS U01 NS100599NINDS NIH HHS U01NS100599NINDS NIH HHS UH2-UH3NS100599NINDS NIH HHS UH3 NS100599
6 · The paper itselfAbstract
objectiveCerebral amyloid angiopathy (CAA) involves β-amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R
methodsCerebral hemispheres from 804 older adults who came to autopsy were included. All hemispheres underwent ex vivo MRI and detailed neuropathologic examination. R
resultsCAA severity was associated with a higher transverse relaxation rate R
interpretationThis is to our knowledge the first investigation of the link between CAA and R
Indexed as
BrainCerebral Amyloid AngiopathyMagnetic Resonance ImagingAgedAged, 80 and overFemaleHumansMaleSeverity of Illness Indexautopsycerebral amyloid angiopathyMRIneuropathologyR2
Identifiers
PMID40244903
PMCPMC12172112
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