Evidence map›Paper›PMID 40244454›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2025

Impact of the COVID-19 pandemic on the respiratory syncytial virus infections in children admitted with community acquired pneumonia: a retrospective study at a tertiary hospital of Northeast China.

Xiaoyi Xu, Leilei Wu, Yi Liu

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Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Xiaoyi Xu *Hongqi Hospital Affiliated to Mudanjiang Medical University, Mudanjiang, Heilongjiang, 157011, China.
Leilei Wu *School of Pharmacy, Mudanjiang Medical University, No. 3, Tongxiang Street, Mudanjiang, Heilongjiang, 157011, China.
Yi LiuSchool of Pharmacy, Mudanjiang Medical University, No. 3, Tongxiang Street, Mudanjiang, Heilongjiang, 157011, China. m13555010829@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe COVID-19 pandemic has markedly altered the infection landscape of various pathogens. This study aimed to evaluate the pandemic's impact on the infection dynamics of respiratory syncytial virus (RSV) among children with community acquired pneumonia (CAP).

methodsPediatric CAP patients were enrolled to compare the prevalence and characteristics of RSV infections before (2018-2019), during (2020-2022), and after (2023) the COVID-19 pandemic.

resultsA total of 991 RSV-positive and 6644 RSV-negative pediatric CAP patients were included. Key findings indicated that RSV-positive patients were younger and had fewer respiratory co-infections with specific pathogens. Following a notable decline in 2019, the RSV positivity rate increased significantly in 2020, then continuously decreased until 2022, and rebounded markedly in 2023. Compared to the pre-pandemic period, there were significant changes in the age distribution, gender composition, and co-infection patterns with specific pathogens among both RSV-positive and RSV-negative patients during and after the pandemic. Seasonal distribution of RSV positive patients and positivity rates in 2018 and 2019 typically peaked in winter. However, the seasonal patterns of RSV positive patients shifted significantly during and after the pandemic, characterized by a sharp decrease in February 2020, no resurgence at the end of 2022, and a delayed peak in April 2023. The seasonal trend of the positivity rate was also disrupted.

conclusionsThe COVID-19 pandemic has profoundly transformed the infection landscape of RSV in pediatric CAP patients, as evidenced by shifts in positivity rates, demographic characteristics, co-infection patterns, and seasonal trends.

Indexed as

Community-Acquired InfectionsCOVID-19PneumoniaRespiratory Syncytial Virus InfectionsAdolescentChildChild, PreschoolChinaCoinfectionCommunity-Acquired PneumoniaFemaleHospitalizationHumansInfantInfant, NewbornMaleCommunity acquired pneumoniaCOVID-19EpidemiologyPediatricsRespiratory syncytial virus

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.