Trial reportArchives of orthopaedic and trauma surgery2025
Effect of mini-open rotator cuff repair combined with intraoperative cocktail therapy in the treatment of rotator cuff injury: a prospective comparative study between the cocktail therapy and the control group.
Trial report in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionTo investigate the clinical effect of mini-open rotator cuff repair combined with intraoperative cocktail therapy in the treatment of rotator cuff injury.
methodsA prospective comparative study of 78 patients with rotator cuff injury who underwent mini-open rotator cuff repair in our hospital from January 2020 to January 2022 and used block randomization to divide patients into 2 groups in this trial: The cocktail group received 150 mg ropivacaine, 40 mg of methylprednisolone succinate, 0.3 mg of epinephrine, and saline solution to a total of 100 mL, whereas the control group received 100mL of saline solution. The drug mixtures were injected into the glenohumeral joint, subacromial bursa, and anterior, middle, and posterior parts of the deltoid muscle. The patients' visual analog scale (VAS) scores preoperatively were recorded at 6, 12, 24, and 48 h postoperatively. We also recorded the Constant-Murley function scores and passive abduction angles of the operation shoulder at two weeks, one, three and six months postoperatively. We also compared the number of patients using postoperative celecoxib capsules and receiving parecoxib sodium injections; the number of patients experiencing nausea; the patients with infection; the course of disease and the tear size.
resultsThe cocktail group constituted 39 shoulders (50.0%), with 16 men (41.0%) and 23 women (59.0%); the mean age was 58.71 ± 6.39 years; the mean BMI was 24.25 ± 4.50 kg/m
conclusionsThe mini-open rotator cuff repair has satisfactory curative effect in the treatment of rotator cuff injury, and intraoperative cocktail therapy can alleviate postoperative pain and speed up postoperative functional rehabilitation and improvement of joint range of motion. LEVEL OF EVIDENCE: Level III, therapeutic study.
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