ArticleSleep & breathing = Schlaf & Atmung2025
Effect of CPAP therapy on vitamin D status in patients with obstructive sleep apnea and chronic obstructive pulmonary disease overlap syndrome.
Article in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Expert consensus on osteoporosis risk management in patients with sleep disorders.Bone research · 2026Review
- Vitamin D Deficiency Is Associated with a Higher 5-Year Risk of Obstructive Sleep Apnea and CPAP Use in Older Adults: An Anchor-Based Network Meta-Analysis.Medicina (Kaunas, Lithuania) · 2026Article
- Improved hemodynamic and cardiorespiratory instability with vitamin D supplementation in an obstructive sleep apnea rat models.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026Article
- Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnea Coexistence: From Pathophysiology to Clinical Complications.International journal of chronic obstructive pulmonary disease · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeVitamin D (Vit D) deficiency has been associated with both obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) as well as with their combination, known as overlap syndrome (OS). There is evidence that continuous positive airway pressure (CPAP) may lead to an increase of Vit D levels in OSA patients. However, the effect of CPAP treatment on Vit D levels in OS patients has yet to be determined. The aim of the present study was to investigate the effect of one year of CPAP therapy on Vit D levels in patients with OS.
methodsVit D serum levels were measured in consecutive OS patients at baseline and after one year of CPAP therapy. Compliance with CPAP therapy was assessed by the data retrieved from the CPAP device.
resultsVit D serum levels were measured in 46 OS patients (43 males). Among participants, 27 had good and 19 poor compliance with CPAP therapy. Results showed that serum Vit D levels increased after 12 months of CPAP therapy from 21.3 ± 8.4 to 23.8 ± 8.7 ng/ml (p = 0.001). Moreover, patients with good CPAP compliance demonstrated higher serum 25(OH)D levels compared to those with poor compliance (25.8 ± 7.6 versus 20.4 ± 9.6 ng/ml, respectively; p = 0.038).
conclusionsIn conclusion, 12 months of CPAP therapy improved Vit D serum levels in OS patients, more so in compliant patients.
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