Evidence map›Paper›PMID 40244315›Full record

ReviewDiscover mental health2025

COVID-19 and cognitive impairment: a review of the emerging evidence.

Nicholas Aderinto, Gbolahan Olatunji, Emmanuel Kokori, Ikponmwosa Jude Ogieuhi, Ismaila Ajayi Yusuf, Emmanuel Egbunu, Bonaventure Michael Ukoaka, Adetola Emmanuel Babalola, Temiloluwa Oluwakorede Adefusi, John Ehi Aboje and 1 more

Abstract readReview
In one paragraph

Review in Discover mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Resting-state functional connectivity and cognitive impairment after COVID-19 infection: Evidence from a large-scale fMRI study.European psychiatry : the journal of the Association of European Psychiatrists · 2026
    Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Brain histopathological changes caused by SARS-CoV-2 infection.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
  13. Neurological symptoms observed in patients with COVID-19.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nicholas AderintoDepartment of Medicine and Surgery, Ladoke Akintola University of Technology, Ogbomoso, Nigeria. nicholasoluwaseyi6@gmail.com.
Gbolahan OlatunjiDepartment of Medicine and Surgery, University of Ilorin, Ilorin, Nigeria.
Emmanuel KokoriDepartment of Medicine and Surgery, University of Ilorin, Ilorin, Nigeria.
Ikponmwosa Jude OgieuhiSiberian State Medical University, Tomsk, Russia.
Ismaila Ajayi YusufObafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.
Emmanuel EgbunuFederal Medical Centre, Bida, Nigeria.
Bonaventure Michael UkoakaDepartment of Internal Medicine, Asokoro District Hospital, Abuja, Nigeria.
Adetola Emmanuel BabalolaFaculty of Dentistry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Temiloluwa Oluwakorede AdefusiDepartment of Medicine & Surgery, College of Health Sciences, Bowen University, Iwo, Nigeria.
John Ehi AbojeCollege of Health Sciences, Benue State University, Makurdi, Benue, Nigeria.
Abdulrahmon MoradeyoDepartment of Medicine and Surgery, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent surge of COVID-19 cases has raised concerns about its potential long-term effects on cognitive function. This review explores the growing body of research investigating the link between COVID-19 infection and cognitive impairment. Studies employing observational, longitudinal, and case-control designs reveal a concerning prevalence of cognitive impairment in survivors, affecting domains like attention, memory, executive function, and processing speed. The persistence of these deficits for months after the initial infection highlights the potential for long-term consequences. While the precise mechanisms remain under investigation, potential contributing factors include neuroinflammation, hypoxia, and psychological effects. Limitations within the current research landscape necessitate further investigation into the long-term trajectory of cognitive decline, the potential for intervention and recovery, and the role of vaccination in mitigating these effects. Understanding the multifaceted nature of this issue is crucial for developing effective strategies to ensure optimal cognitive health outcomes for COVID-19 survivors.

Indexed as

AttentionCognitive declineCognitive impairmentCOVID-19

Identifiers

PMID40244315
PMCPMC12006571

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.