Evidence map›Paper›PMID 40244254›Full record

SynthesisInternational journal of molecular sciences2025

Single-Nucleotide Polymorphisms Related to Multiple Myeloma Risk: A Systematic Review and Meta-Analysis.

Giovanna Gilioli da Costa Nunes, Francisco Cezar Aquino de Moraes, Aline Beatriz Carvalho de Almeida, Felipe Goes Costa, Luiz Fernando Duarte de Andrade Junior, Maria Vitória Sabino Hupp, Ruan Rotondano Assunção, Marianne Rodrigues Fernandes, Sidney Emanuel Batista Dos Santos, Ney Pereira Carneiro Dos Santos

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. FokI Polymorphism of theNutrients · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giovanna Gilioli da Costa NunesResearch Center of Oncology, Federal University of Pará Belém, Belém 66073-000, PA, Brazil.
Francisco Cezar Aquino de MoraesResearch Center of Oncology, Federal University of Pará Belém, Belém 66073-000, PA, Brazil.
Aline Beatriz Carvalho de AlmeidaResearch Center of Oncology, Federal University of Pará Belém, Belém 66073-000, PA, Brazil.ORCID 0009-0001-6714-6165
Felipe Goes CostaResearch Center of Oncology, Federal University of Pará Belém, Belém 66073-000, PA, Brazil.
Luiz Fernando Duarte de Andrade JuniorResearch Center of Oncology, Federal University of Pará Belém, Belém 66073-000, PA, Brazil.
Maria Vitória Sabino HuppResearch Center of Oncology, Federal University of Pará Belém, Belém 66073-000, PA, Brazil.
Ruan Rotondano AssunçãoFaculty of Medicine, Federal University of Pará Belém, Belém 66073-000, PA, Brazil.
Marianne Rodrigues FernandesResearch Center of Oncology, Federal University of Pará Belém, Belém 66073-000, PA, Brazil.ORCID 0000-0002-1396-3442
Sidney Emanuel Batista Dos SantosLaboratory of Human and Medical Genetics, Institute of Biological Science, Federal University of Pará Belém, Belém 66077-830, PA, Brazil.ORCID 0000-0002-8622-9417
Ney Pereira Carneiro Dos SantosResearch Center of Oncology, Federal University of Pará Belém, Belém 66073-000, PA, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma ranks as the second most common hematopoietic malignancy in terms of both incidence and mortality. Prognostic stratification is critical for optimizing therapeutic strategies, as certain genetic alterations can significantly influence disease progression and treatment response. The meta-analysis analyzed data from 3421 multiple myeloma patients and 14,720 controls. PubMed, Web of Science, and Scopus were used as databases. Associations between the SNPs and multiple myeloma were calculated as a measure of pooled odds ratios (ORs) and 95% confidence intervals. Statistical analysis was performed using Review Manager (RevMan).

Indexed as

Genetic Predisposition to DiseaseMultiple MyelomaPolymorphism, Single NucleotideGenotypeHumansRisk Factorsepidemiologymultiple myelomarisksingle-nucleotide polymorphism

Identifiers

PMID40244254
PMCPMC11989572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.