ArticleInternational journal of molecular sciences2025
From Genes to Disease: Reassessing
Tatiana Romanovna Tsedilina, Elena Ivanovna Sharova, Alexandra Vasilevna Kanygina, Boris Eduardovich Malyugin, Olga Pavlovna Antonova, Alexandra Vladimirovna Belodedova, Ivan Sergeevich Tkachenko, Aslan Mukhtarovich Gelyastanov, Andrey Vladimirovich Zolotarev, Aleksey Vladimirovich Klokov and 4 more
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Tatiana Romanovna TsedilinaMedical Genomics Laboratory, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of the Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0002-4335-4154 Elena Ivanovna SharovaMedical Genomics Laboratory, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of the Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0003-3208-9719 Alexandra Vasilevna KanyginaMedical Genomics Laboratory, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of the Federal Medical Biological Agency, 119435 Moscow, Russia.
Boris Eduardovich MalyuginThe Jules Stein Eye Institute, University of California at Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0001-5666-3493 Olga Pavlovna AntonovaDepartment of Anterior Segment Transplant and Optical Reconstructive Surgery, S. Fyodorov Eye Microsurgery Complex Federal State Institution, 127486 Moscow, Russia.
Alexandra Vladimirovna BelodedovaDepartment of Anterior Segment Transplant and Optical Reconstructive Surgery, S. Fyodorov Eye Microsurgery Complex Federal State Institution, 127486 Moscow, Russia.
Ivan Sergeevich TkachenkoDepartment of Anterior Segment Transplant and Optical Reconstructive Surgery, S. Fyodorov Eye Microsurgery Complex Federal State Institution, 127486 Moscow, Russia.
Aslan Mukhtarovich GelyastanovDepartment of Anterior Segment Transplant and Optical Reconstructive Surgery, S. Fyodorov Eye Microsurgery Complex Federal State Institution, 127486 Moscow, Russia.
Andrey Vladimirovich ZolotarevSamara Regional Clinical Ophthalmological Hospital named after T.I. Yeroshevsky, 443068 Samara, Russia.
Aleksey Vladimirovich KlokovKrasnodar Branch, S. Fyodorov Eye Microsurgery Complex Federal State Institution, 350012 Krasnodar, Russia.
Aleksandr Olegovich MurashevOphthalmology Clinical Centre "Bio Absolut", 601909 Kovrov, Russia.
Irina Viktorovna FedyushkinaLaboratory of Human Molecular Genetics, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of the Federal Medical Biological Agency, 119435 Moscow, Russia.
Edward Viktorovich GenerozovLaboratory of Human Molecular Genetics, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of the Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0002-6314-4883 Liubov Olegovna SkorodumovaMedical Genomics Laboratory, Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of the Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0002-7747-2730 Funding
Russian Science Foundation 22-75-10157
6 · The paper itselfAbstract
Fuchs' endothelial corneal dystrophy (FECD) is a genetically complex eye disease associated with multiple genes. A recent systematic review has raised concerns about the causal role of variants in the
Indexed as
Fuchs' Endothelial DystrophyGenetic Predisposition to DiseaseScavenger Receptors, Class EEndothelium, CornealFemaleHumansMaleMiddle AgedScavenger Receptors, Class EAGBL1 variantsFECDFuchs’ dystrophyLOXHD1 variants
Identifiers
PMID40244234
PMCPMC11989410
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